195324-59-5

Basic information

• Product Name: Phosphonic acid, (3-oxo-1,3-diphenylpropyl)-, diethyl ester
• CAS NO: 195324-59-5
• Molecular Formula: C19H23O4P
• Molecular Weight: 346.363
• Mol File: 195324-59-5.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, (3-oxo-1,3-diphenylpropyl)-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, (3-oxo-1,3-diphenylpropyl)-, diethyl ester(195324-59-5)
• EPA Substance Registry System: Phosphonic acid, (3-oxo-1,3-diphenylpropyl)-, diethyl ester(195324-59-5)

Safety Data

• Hazardous Substances Data: 195324-59-5(Hazardous Substances Data)

Upstream product

• 1817-49-8 1,3-diphenyl-1-propyn-3-ol 
• 762-04-9 Diethyl phosphonate 
• 94-41-7 benzalacetophenone 
• 762-04-9 phosphonic acid diethyl ester 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 122-52-1 triethyl phosphite 
• 64-17-5 ethanol 

Relevant articles and documents

Potassium carbonate promoted nucleophilic addition of alkenes with phosphites

A facile hydrophosphonylation of alkenes by phosphites promoted by potassium carbonate was developed. The reaction features include easy handling, environmental friendliness, and avoidance of the use of strong bases. A variety of alkenes are tolerated in this reaction, with moderate to excellent yields.

Generation and Application of Homoenolate Equivalents Utilizing [1,2]-Phospha-Brook Rearrangement under Br?nsted Base Catalysis

A new method for catalytic generation of a homoenolate equivalent and its application to carbon?carbon bond formation was developed by utilizing the [1,2]-phospha-Brook rearrangement under Br?nsted base catalysis. The α-oxygenated allyl anions, which can

N -BuLi as a highly efficient precatalyst for hydrophosphonylation of aldehydes and unactivated ketones

It was found for the first time that organic alkali metal compounds serve as highly efficient precatalysts for the hydrophosphonylation reactions of aldehydes and unactivated ketones with dialkyl phosphite under mild conditions. For ketone substrates, a reversible reaction was observed, and the influence of catalyst loading and reaction temperature on the reaction equilibrium was studied in detail. Overall, the hydrophosphonylation reactions catalyzed by 0.1 mol % n-BuLi were completed within 5 min for a broad range of substrates and generated a series of α-hydroxy phosphonates in high yields.