195393-28-3Relevant articles and documents
Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents
Wright,Addae-Kyereme,Breen,Brown,Cox,Croft,G?k?ek,Kendrick,Phillips,Pollet
, p. 3187 - 3194 (2001)
The indoloquinoline alkaloid cryptolepine 1 has potent in vitro antiplasmodial activity, but it is also a DNA intercalator with cytotoxic properties. We have shown that the antiplasmodial mechanism of 1 is likely to be due, at least in part, to a chloroqu