19549-84-9

Basic information

• Product Name: 3,5-DIMETHYL-4-HEPTANONE
• Synonyms: 3,5-dimethylheptan-4-one;4-Heptanone, 3,5-dimethyl-;4-Heptanone,3,5-dimethyl-;Di-sec-butylketone;3,5-DIMETHYL-4-HEPTANONE;3,5-DIMETHYL-4-HEPTANONE 97%;3,5-Dimethyl-4-heptanone,97%
• CAS NO: 19549-84-9
• Molecular Formula: C₉H₁₈O
• Molecular Weight: 142.24
• EINECS: 243-150-4
• Mol File: 19549-84-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: -18.52°C (estimate)
• Boiling Point: 162 °C
• Flash Point: 46 °C
• Appearance: clear colourless liquid
• Density: 0.826
• Vapor Pressure: 2.21mmHg at 25°C
• Refractive Index: 1.4154-1.4174
• Storage Temp.: Flammables area
• CAS DataBase Reference: 3,5-DIMETHYL-4-HEPTANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIMETHYL-4-HEPTANONE(19549-84-9)
• EPA Substance Registry System: 3,5-DIMETHYL-4-HEPTANONE(19549-84-9)

Safety Data

• Statements: 10
• Safety Statements: 16
• RIDADR: 1224
• HazardClass: 3.2
• PackingGroup: III
• Hazardous Substances Data: 19549-84-9(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR COLOURLESS LIQUID

InChI:InChI=1/C9H18O/c1-5-7(3)9(10)8(4)6-2/h7-8H,5-6H2,1-4H3/t7-,8-/m0/s1

Upstream product

• 4784-77-4 (E/Z)-crotyl bromide 
• 34575-26-3 2-(sec-butyl)-4,4-dimethyl-2-oxazoline 
• 5325-94-0 N-Ethoxycarbonylpiperidine 
• 598-30-1 sec.-butyllithium 
• 116-53-0 2-Methylbutanoic acid 
• 75844-69-8 t-butyl piperidinecarboxylate 
• 67-56-1 methanol 
• 123-19-3 4-heptanone 
• 74-88-4 methyl iodide 
• 78-86-4 s-butyl chloride 
• 5856-79-1 iso-butyl chloroformate 
• 107-01-7 butene-2 
• 4885-02-3 Dichloromethyl methyl ether 
• 75-03-6 ethyl iodide 

Downstream Products

• 19549-79-2 3,5-dimethylheptan-4-ol 

Relevant articles and documents

Application of catalytic dynamic resolution of N-Boc-2-lithiopiperidine to the asymmetric synthesis of 2-aryl and 2-vinyl piperidines

The highly enantioselective synthesis of 2-aryl-and 2-vinyl-piperidines has been accomplished through a catalytic dynamic resolution (CDR) of N-Boc-2-lithiopiperidine. The method has been applied to the synthesis of both enantiomers of the tobacco alkaloid anabasine.

N-CARBOETHOXYPIPERIDINE, A CONVENIENT REAGENT FOR THE PREPARATION OF SYMMETRICAL KETONES FROM ORGANOLITHIUMS

N-Carboethoxypiperidine on reaction with organolithium reagents, RLi, followed by acidic work-up gave excellent yields of the corresponding symmetrical ketones, R2CO.

α-Methylation of ketones via manganese-enolates: Absence of undesired polyalkylation

The transmetalation of ketone lithium-enolates using MnBr2 generates manganese-enolates which react with CH3I to provide α-methylated ketones with essentially no undesired polyalkylated byproducts.