19577-83-4 Usage
General Description
2-Piperidin-1-ylmethyl-aniline is a chemical compound with the molecular formula C13H19N. It is a substituted aniline with a piperidine group at the 2-position. 2-Piperidin-1-ylmethyl-aniline is commonly used as an intermediate in the synthesis of pharmaceuticals and organic chemicals. It is also used as a building block in the production of various functional materials, such as dyes, pigments, and polymers. 2-Piperidin-1-ylmethyl-aniline is considered to be a potentially hazardous substance and requires proper handling and storage to prevent harmful exposure. Its chemical properties and structure make it a valuable tool for the development of new compounds and materials in the field of chemistry and pharmaceutical science.
Check Digit Verification of cas no
The CAS Registry Mumber 19577-83-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,5,7 and 7 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 19577-83:
(7*1)+(6*9)+(5*5)+(4*7)+(3*7)+(2*8)+(1*3)=154
154 % 10 = 4
So 19577-83-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H18N2/c13-12-7-3-2-6-11(12)10-14-8-4-1-5-9-14/h2-3,6-7H,1,4-5,8-10,13H2
19577-83-4Relevant articles and documents
Redox Condensations of o-Nitrobenzaldehydes with Amines under Mild Conditions: Total Synthesis of the Vasicinone Family
Afanasyev, Oleg I.,Podyacheva, Evgeniya,Rudenko, Alexander,Tsygankov, Alexey A.,Makarova, Maria,Chusov, Denis
, p. 9347 - 9360 (2020/08/14)
A total synthesis of the vasicinone family of natural products from bulk chemicals was developed. Reductive condensation of o-nitrobenzaldehydes with amines utilizing iron pentacarbonyl as a reducing agent followed by subsequent oxidation leads to a great variety of polycyclic nitrogen-containing heterocycles under mild conditions. Enantiomerically pure vasicinone, rutaecarpine, isaindigotone, and luotonin were synthesized from readily available starting materials like hydroxyproline, nitrobenzaldehyde, pyrrolidine, and piperidine in two to four operational steps without chromatography. The antifungal activity of all products was tested.
