195812-68-1 Usage
General Description
ISOPROPYL 3-ACETYLPYRIDINE-2-CARBOXYLATE is a chemical compound that belongs to the class of pyridine carboxylates. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. ISOPROPYL 3-ACETYLPYRIDINE-2-CARBOXYLATE is known for its ability to act as a building block for various organic reactions and is often used in the production of drugs and crop protection agents. Its chemical structure consists of a pyridine ring with an acetyl group and an isopropyl ester of the carboxylic acid, making it a valuable and versatile compound in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 195812-68-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,5,8,1 and 2 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 195812-68:
(8*1)+(7*9)+(6*5)+(5*8)+(4*1)+(3*2)+(2*6)+(1*8)=171
171 % 10 = 1
So 195812-68-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H13NO3/c1-7(2)15-11(14)10-9(8(3)13)5-4-6-12-10/h4-7H,1-3H3
195812-68-1Relevant articles and documents
Two non-racemic preparations of a piperidine-based NMDA antagonist with analgesic activity
Swahn, Britt-Marie,Edvinsson, Karin M.,Kallin, Elisabet,Larsson, Ulf,Berge, Odd-Geir,Molin, Hakan,Pelcman, Benjamin,Claesson, Alf
, p. 1293 - 1299 (1997)
(2R,3S,1'R)-3-(1-Hydroxy-2-phosphonoethyl)-2-piperidinecarboxylic acid 1 has been synthesized by two different methods. The NMDA receptor binding affinities (K(i) values) are 74 nM for compound 1, and 64 nM for the corresponding ketone 2. The analgesic effects were evaluated using the mouse hot-plate test and the mouse formalin model. The ED50 values for the racemates of compounds 1 and 2, using the mouse hotplate and intrathecal injection, were 0.53 and 0.51 nmol, respectively.
