196106-48-6

Basic information

• Product Name: (R)-2-acetoxy-2-(3'-chlorophenyl)acetic acid
• Synonyms: (R)-2-acetoxy-2-(3'-chlorophenyl)acetic acid
• CAS NO: 196106-48-6
• Molecular Weight: 228.632
• Mol File: 196106-48-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-2-acetoxy-2-(3'-chlorophenyl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-acetoxy-2-(3'-chlorophenyl)acetic acid(196106-48-6)
• EPA Substance Registry System: (R)-2-acetoxy-2-(3'-chlorophenyl)acetic acid(196106-48-6)

Safety Data

• Hazardous Substances Data: 196106-48-6(Hazardous Substances Data)

Upstream product

• 947156-24-3 2-acetoxy-2-(3-chlorophenyl)acetic acid 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 16273-37-3 (R)-3-chloromandelic acid 

Relevant articles and documents

Enantioselective C-H Olefination of α-Hydroxy and α-Amino Phenylacetic Acids by Kinetic Resolution

Significant progress has been made in the past decade regarding the development of enantioselective C-H activation reactions by desymmetrization. However, the requirement for the presence of two chemically identical prochiral C-H bonds represents an inherent limitation in scope. Reported is the first example of kinetic resolution by a palladium(II)-catalyzed enantioselective C-H activation and C-C bond formation, thus significantly expanding the scope of enantioselective C-H activation reactions.