196298-73-4

Basic information

• Product Name: [3-[3-fluoro-4-(1H-imidazol-1-yl)phenyl]-2-oxo-5-oxazolidinyl]methanol
• Synonyms: [3-[3-fluoro-4-(1H-imidazol-1-yl)phenyl]-2-oxo-5-oxazolidinyl]methanol
• CAS NO: 196298-73-4
• Molecular Weight: 277.255
• Mol File: 196298-73-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [3-[3-fluoro-4-(1H-imidazol-1-yl)phenyl]-2-oxo-5-oxazolidinyl]methanol(CAS DataBase Reference)
• NIST Chemistry Reference: [3-[3-fluoro-4-(1H-imidazol-1-yl)phenyl]-2-oxo-5-oxazolidinyl]methanol(196298-73-4)
• EPA Substance Registry System: [3-[3-fluoro-4-(1H-imidazol-1-yl)phenyl]-2-oxo-5-oxazolidinyl]methanol(196298-73-4)

Safety Data

• Hazardous Substances Data: 196298-73-4(Hazardous Substances Data)

Upstream product

• 154164-56-4 3-fluoro-4-(1H-imidazol-1-yl)nitrobenzene 
• 190200-19-2 3-fluoro-4-(1H-imidazol-1-yl)phenylamine 
• 369-34-6 3,4-difluoronitrobenzene 
• 60456-26-0 (R)-glycidyl butyrate 
• 181997-10-4 3-fluoro-4-(1H-imidazol-1-yl)-1-(phenylmethoxycarbonylamino)benzene 

Downstream Products

• 371195-22-1 (5R)-3-(4-Imidazol-1-yl-3-fluorophenyl)-5-methanesulfonyloxymethyloxazolidin-2-one 
• 343880-92-2 (S)-5-aminomethyl-3-[3-fluoro-4-(1-imidazolyl)phenyl]oxazolidine-2-one 
• 196298-77-8 (5R)-3-(4-Imidazol-1-yl-3-fluorophenyl)-5-azidomethyloxazolidin-2-one 
• 264600-51-3 5(R)-(N-(2,2,2-trichloroethyloxycarbonyl)-isoxazol-3-ylaminomethyl)-3-(4-imidazol-1-yl-3-fluorophenyl)oxazolidin-2-one 

Relevant articles and documents

Design and synthesis of novel 5-acetylthiomethyl oxazolidinone analogs

The oxazolidinone class of antimicrobial agents represents a promising advance in the fight against resistant Gram-positive bacterial infections. To improve antibacterial activity and expand the spectrum of activity including Gram-negative bacteria, a series of novel 5-acetylthiomethyl oxazolidinone analogs were designed and synthesized based on the structure-activity relationship studies. The structures of the target compounds and main intermediates were confirmed by 1H NMR, 13C NMR, infrared (IR), mass spectra (MS), and elemental analysis.