19647-68-8 Usage
General Description
"(S)-benzyl 3-hydroxy-1-(methylamino)-1-oxopropan-2-ylcarbamate" is a specific chemical compound. As the name suggests, it contains an organic functional group called carbamate along with a benzyl group, a methylamino group, and a hydroxyl group. The alanine-based structure shows stereochemistry, indicated by the "(S)" at the beginning of its name, implying that there is a specific arrangement of atoms in space. The oxopropan structure indicates the presence of a ketone functionality. Detailed properties such as its physical characteristics, chemical reactivity, toxicity, and applications would vary and would be determined based on empirical research. It seems this compound could potentially be aimed at pharmaceutical applications due to the healthcare-related functionalities, but the exact applications and relevancy would require further information and research.
Check Digit Verification of cas no
The CAS Registry Mumber 19647-68-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,6,4 and 7 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 19647-68:
(7*1)+(6*9)+(5*6)+(4*4)+(3*7)+(2*6)+(1*8)=148
148 % 10 = 8
So 19647-68-8 is a valid CAS Registry Number.
19647-68-8Relevant articles and documents
Reactivity of amino acid side chain groups. II. N-acetyl methylam des of threonine and hydroxyproline
Zahn,Reinert
, p. 608 - 610 (1968)
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Efficient synthesis of (R)-6-benzyloxycarbonylamino-1-methyl-4-(3- methylbenzyl)hexahydro-1,4-diazepine. I
Harada, Hiroshi,Morie, Toshiya,Kato, Shiro
, p. 1160 - 1164 (2007/10/03)
An efficient and practical method for large scale synthesis of (R)-6- benzyloxycarbonylamino-1-methyl-4-(3-methylbenzyl)hexahydro-1,4-diazepine (R- 3), which is a key intermediate in the synthesis of DAT-582, a potent and selective serotonin-3 receptor antagonist, is described. The precursor of R- 3, the (S)-2,3-diaminopropylaminoacetate S-5, was obtained from the chiral triaminopropane derivative R-19. Nucleophilic reaction of the chiral mesylate R-11 with 3-methylbenzylamine gave the racemic 2,3-diaminopropylaminoacetate (±)-5 via the achiral azetidinium cation 12, while the reaction of the N- protected mesylate R-14 produced the desired triamine S-15 but in poor yield. However, reaction of the N-protected mesylate S-18 with a large excess of methylamine proceeded smoothly to afford R-19 in good yield. S-5 was converted into R-3 with >99% enantiomeric excess using an intramolecular reductive cyclization method.
