196600-09-6

Basic information

• Product Name: (Z)-(4-methoxyphenoxy)-3-methylpent-2-en-4-yne
• CAS NO: 196600-09-6
• Molecular Weight: 202.253
• Mol File: 196600-09-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-(4-methoxyphenoxy)-3-methylpent-2-en-4-yne(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-(4-methoxyphenoxy)-3-methylpent-2-en-4-yne(196600-09-6)
• EPA Substance Registry System: (Z)-(4-methoxyphenoxy)-3-methylpent-2-en-4-yne(196600-09-6)

Safety Data

• Hazardous Substances Data: 196600-09-6(Hazardous Substances Data)

Upstream product

• 6153-05-5 (Z)-3-methylpent-2-en-4-ynol 
• 150-76-5 4-methoxy-phenol 

Downstream Products

• 196600-23-4 (Z)-1-[5-(4-methoxyphenoxy)-3-methylpent-3-en-1-yn-1-yl]-2,5-dimethoxy-3,4,6-trimethylbenzene 

Relevant articles and documents

Enantioselective synthesis of chromans for the preparation of enantiopure vitamin E and analogues

Coupling of the differently protected (hydroxymethyl)enynes 11 a-e and 12a-c with the iodoarene 7 in the presence of catalytic amounts of Pd(PPh3)4 afforded the arylenynes 5a-e and 6a-c which were transformed into the monoprotected chiral trihydroxy compounds 13 a-d and 14a,b by Sharpless bishydroxylation with >95% ee for 13 a-d, 91% ee for 14b, and 64% ee for 14a. A 5-step transformation of 13a led to the desired chroman derivative 3a which was cleaved to give the aldehyde 2 a known precursor for the enantioselective synthesis of vitamin E.