196698-26-7

Basic information

• Product Name: ethyl 2,2-dichloro-4,4,4-trifluoro-3-oxobutanoate
• CAS NO: 196698-26-7
• Molecular Weight: 253.005
• Mol File: 196698-26-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2,2-dichloro-4,4,4-trifluoro-3-oxobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2,2-dichloro-4,4,4-trifluoro-3-oxobutanoate(196698-26-7)
• EPA Substance Registry System: ethyl 2,2-dichloro-4,4,4-trifluoro-3-oxobutanoate(196698-26-7)

Safety Data

• Hazardous Substances Data: 196698-26-7(Hazardous Substances Data)

Upstream product

• 1522-43-6 ethyl 3-oxo-4,4,4-trifluorobutanoate enol 

Downstream Products

• 117724-63-7 2-methyl-4-trifluoromethylthiazole-5-carboxylic acid 

Relevant articles and documents

Halogenation of fluorinated cyclic 1,3-dicarbonyl compounds: new aspects of synthetic application

In order to elaborate on an approach towards 2-(fluoroacyl)phenols being the superior alternative to the conventional Fries-rearrangement based methodology, the behaviour of cyclic fluorinated 1,3-dicarbonyls in reactions with halogenating agents was examined. The synthetic relevance of the polyhalogenated compounds obtained was demonstrated by the synthesis of several new heterocycles. An aromatization via a halogenation-dehydrohalogenation sequence proved to be a rewarding synthetic route to 2-(fluoroacyl)phenols and previously unknown 3-(fluoroacyl)thiochromones. The structure of one of the synthesized compounds was confirmed by X-ray diffraction analysis.