1969-09-1Relevant articles and documents
Thiosemicarbazide Derivatives as Building Block in Synthesis of Target Heterocyclic Compounds with Their Antimicrobial Assessment
Abou Elmagd, Wael S. I.,Hemdan, Magdy M.,Samy, Sandy S.,Youssef, Ahmed S. A.
, p. 1391 - 1395 (2017/03/27)
1-(2-Benzamido-3-(1,3-diphenyl-1H-pyrazol-4-yl)acryloyl)-4-phenylthiosemicarbazide is used as precursor for synthesis of imidazole, 1,3,4-oxadiazole, 1,3,4-thiadiazole, 1,3-oxazine, and 1,2,4-triazine ring systems. The antimicrobial activity of some of th
Synthesis of 2-amino-1,3,4-oxadiazoles from isoselenocyanates via cyclodeselenization
Xie, Yuanyuan,Liu, Junli,Yang, Ping,Shi, Xiangjun,Li, Jianjun
experimental part, p. 5369 - 5374 (2011/07/31)
An efficient one-pot method to access 2-amino-1,3,4-oxadiazoles from isoselenocyanates and hydrazides or dihydrazides was developed via cyclodeselenization. Without any harsh reagents, various 2-amino-1,3,4- oxadiazoles were obtained in considerably high
Superior reactivity of thiosemicarbazides in the synthesis of 2-amino-1,3,4-oxadiazoles
Dolman, Sarah J.,Gosselin, Francis,O'Shea, Paul D.,Davies, Ian W.
, p. 9548 - 9551 (2007/10/03)
(Chemical Equation Presented) A facile and general protocol for the preparation of 2-amino-1,3,4-oxadiazoles is reported. This method relies on a tosyl chloride/pyridine-mediated cyclization of a thiosemicarbazide, which is readily prepared by acylation o
