1970-56-5

Basic information

• Product Name: p-methoxy-α-bromoisobutyranilide
• Synonyms: p-methoxy-α-bromoisobutyranilide
• CAS NO: 1970-56-5
• Molecular Weight: 272.142
• Mol File: 1970-56-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: p-methoxy-α-bromoisobutyranilide(CAS DataBase Reference)
• NIST Chemistry Reference: p-methoxy-α-bromoisobutyranilide(1970-56-5)
• EPA Substance Registry System: p-methoxy-α-bromoisobutyranilide(1970-56-5)

Safety Data

• Hazardous Substances Data: 1970-56-5(Hazardous Substances Data)

Upstream product

• 20769-85-1 2-bromoisobutyric acid bromide 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 35844-02-1 p-methoxy-α-nitroisobutyranilide 
• 7274-71-7 N-(4-methoxyphenyl)-2-methylacrylamide 
• 85576-95-0 N-(4-Methoxy-phenyl)-N-[1-(4-methoxy-phenylcarbamoyl)-1-methyl-ethyl]-2-methyl-acrylamide 
• 128966-11-0 3-(4-Methoxyphenyl)-5,5-dimethyl-2-dimethylaminooxazolidin-4-one 

Relevant articles and documents

Bromo-nitro substitution on a tertiary α carbon - A previously uncharacterized facet of the Kornblum substitution

Sodium nitrite in dimethylformamide substitutes nitro for bromine alpha to an amide carbonyl in high yield at a tertiary site. Hammett plots show a strongly positive ρ value (+0.67), indicating a negatively-charged transition state, in contrast to the typical SN1/SN2 mechanism domain for Kornblum substitutions. 2015

Synthesis and evaluation of the local anesthetic activity of a series of aliphatic amino acid anilides

-