19701-85-0

Basic information

• Product Name: 2-Pyrrolidinecarboxamide,1-acetyl-N-methyl-,(2S)-(9CI)
• Synonyms: 2-Pyrrolidinecarboxamide,1-acetyl-N-methyl-,(2S)-(9CI)
• CAS NO: 19701-85-0
• Molecular Formula: C8H14N2O2
• Molecular Weight: 170.21
• Product Categories: PYRROLE
• Mol File: 19701-85-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 411.3°Cat760mmHg
• Flash Point: 202.6°C
• Appearance: /
• Density: 1.126g/cm³
• Vapor Pressure: 5.63E-07mmHg at 25°C
• Refractive Index: 1.494
• CAS DataBase Reference: 2-Pyrrolidinecarboxamide,1-acetyl-N-methyl-,(2S)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinecarboxamide,1-acetyl-N-methyl-,(2S)-(9CI)(19701-85-0)
• EPA Substance Registry System: 2-Pyrrolidinecarboxamide,1-acetyl-N-methyl-,(2S)-(9CI)(19701-85-0)

Safety Data

• Hazardous Substances Data: 19701-85-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H14N2O2/c1-6(11)10-5-3-4-7(10)8(12)9-2/h7H,3-5H2,1-2H3,(H,9,12)

Upstream product

• 74-89-5 methylamine 
• 68-95-1 (S)-acetylproline 
• 108-24-7 acetic anhydride 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 88815-87-6 tert-butyl (2S)-2-(methylcarbamoyl)pyrrolidine-1-carboxylate 
• 52060-82-9 L-proline methylamide 
• 147-85-3 L-proline 

Relevant articles and documents

Effects of glycosylation of (2S,4R)-4-hydroxyproline on the conformation, kinetics, and thermodynamics of prolyl amide isomerization

Glycosylation (galactosylation) of (2S,4R)-4-hydroxyproline (Hyp) in the peptide mimic N-acetyl-Hyp-N′-methylamide does not mediate the isomer equilibrium nor the rate of isomerization between the cis- and trans-prolyl amides in water. However, glycosylat

Solution structural features of N-acyl homoserine lactones

Here we demonstrate that in interbacterial quorum signal moderators, N-acylhomoserine lactones (AHLs), the stabilization of bioactive pharmacophore lactone against lysis is through the e- withdrawing N-acyl motif which reduces lactone carbonyl polarization. This lysis is assisted by weak (-1) contacts between N-acyl O and lactone C′. The interactions that preclude this weak contact, in the free and receptor-bound AHLs, improve lactone halflife and hence are key to the design of the antibacterial AHL analogues.