19715-80-1

Basic information

• Product Name: CHEMBRDG-BB 6617565
• Synonyms: CHEMBRDG-BB 6617565;2-(4-bromophenyl)-N,N-dimethylacetamide;benzeneacetamide, 4-bromo-N,N-dimethyl-;Albb-009557;2-(4-bromophenyl)-N,N-dimethylacetamide(SALTDATA: FREE);2-(4-bromophenyl)-N,N-dimethyl-ethanamide
• CAS NO: 19715-80-1
• Molecular Formula: C₁₀H₁₂BrNO
• Molecular Weight: 242.12
• Product Categories: alkyl bromide
• Mol File: 19715-80-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 335.9°C at 760 mmHg
• Flash Point: 156.9°C
• Appearance: /
• Density: 1.377g/cm³
• Vapor Pressure: 0.000116mmHg at 25°C
• Refractive Index: 1.555
• CAS DataBase Reference: CHEMBRDG-BB 6617565(CAS DataBase Reference)
• NIST Chemistry Reference: CHEMBRDG-BB 6617565(19715-80-1)
• EPA Substance Registry System: CHEMBRDG-BB 6617565(19715-80-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 19715-80-1(Hazardous Substances Data)

Usage

Description

CHEMBRDG-BB 6617565, also known as 2-(4-Bromophenyl)-N,N-dimethylacetamide (cas# 19715-80-1), is a chemical compound that has been identified for its potential applications in various fields, particularly in the development of pharmaceuticals and materials science. It is characterized by its unique molecular structure, which allows it to interact with other molecules and exhibit specific properties.

Uses

Used in Pharmaceutical Industry:
CHEMBRDG-BB 6617565 is used as an intermediate compound for the preparation of bicyclic pyridine compositions. These compositions have potential applications in cancer therapy, making it a valuable component in the development of novel anticancer drugs.
Used in Materials Science:
The unique molecular structure of CHEMBRDG-BB 6617565 also makes it a candidate for use in materials science, where it can be employed to create new materials with specific properties or to modify existing materials for improved performance.

InChI:InChI=1/C10H12BrNO/c1-12(2)10(13)7-8-3-5-9(11)6-4-8/h3-6H,7H2,1-2H3

Upstream product

• 124-40-3 dimethyl amine 
• 1878-68-8 2-(4-bromophenyl)-acetic acid 
• 589-17-3 p-bromobenzyl chloride 
• 479486-96-9 N,N-dimethyl (trimethylsilyl)methanamide 
• 68-12-2 N,N-dimethyl-formamide 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 589-87-7 1,4-bromoiodobenzene 
• 79-37-8 oxalyl dichloride 
• 506-59-2 N,N-dimethylammonium chloride 

Downstream Products

• 868065-77-4 tert-butyl 4-{4-[2-(dimethylamino)-2-oxoethyl]phenyl}piperazine-1-carboxylate 
• 15221-61-1 2-(4-bromophenyl)-N,N-dimethylethan-1-amine 
• 868066-58-4 2-[4-(1,4-diazepan-1-yl)phenyl]-N,N-dimethylacetamide 
• 868066-54-0 3-amino-4-(4-(4-(2-(dimethylamino)-2-oxoethyl)phenyl)-1,4-diazepan-1-yl)thieno[2,3-b]pyridine-2-carboxamide 
• 868066-60-8 2-{4-[4-(3-cyano-2-thioxo-1,2-dihydropyridin-4-yl)-1,4-diazepan-1-yl]phenyl}-N,N-dimethylacetamide 
• 868066-56-2 benzyl 4-{4-[2-(dimethylamino)-2-oxoethyl]phenyl}-1,4-diazepane-1-carboxylate 
• 697746-46-6 3-[4-(N,N-dimethylcarbamoylmethyl)phenyl]-5-iso-butyl-N-tert-butyl-thiophene-2-sulfonamide 
• 93413-91-3 1-<(4-bromophenyl)<(dimethylamino)carbonyl>methyl>cyclohexanol 

Relevant articles and documents

Amidation reaction of carboxylic acid with formamide derivative using SO3?pyridine

The amidation reaction of carboxylic acid derivatives was developed using sulfur trioxide pyridine complex (SO3?py) as a commercially available and easily handled oxidant. This method could be applied to the reaction of various aromatic and aliphatic carboxylic acids, including optically active ones, with formamide derivatives to afford the corresponding amides in good to high yields.

Catalytic Enantioselective α-Fluorination of 2-Acyl Imidazoles via Iridium Complexes

The first highly enantioselective α-fluorination of 2-acyl imidazoles utilizing iridium catalysis has been accomplished. This transformation features mild conditions and a remarkably broad substrate scope, providing an efficient and highly enantioselective approach to obtain a wide range of fluorine-containing 2-acyl imidazoles which are found in a variety of bioactive compounds and prodrugs. A large scale synthesis has also been tested to demonstrate the potential utility of this fluorination method.

COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE

Compounds of formula (I) and salts and solvates are provided: formula (I). Processes for preparation, pharmaceutical compositions, and uses thereof as a medicament, for example in the treatment of a disease or condition mediated by a reduction or imbalance in glutamate receptor function, such as schizophrenia or cognition impairment, are also disclosed.