197312-72-4

Basic information

• Product Name: C₁₆H₂₆O₂Si
• Synonyms: C₁₆H₂₆O₂Si
• CAS NO: 197312-72-4
• Molecular Weight: 278.467
• Mol File: 197312-72-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: C₁₆H₂₆O₂Si(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₂₆O₂Si(197312-72-4)
• EPA Substance Registry System: C₁₆H₂₆O₂Si(197312-72-4)

Safety Data

• Hazardous Substances Data: 197312-72-4(Hazardous Substances Data)

Upstream product

• 3880-99-7 1-(13C)benzoic acid 
• 35576-31-9 2-phenyl-<2-13C>-1,3-dithian 
• 149063-93-4 triisopropylbromosilane 
• 65-85-0 benzoic acid 
• 6485-79-6 chlorotriisopropylsilane 
• 13154-24-0 triisopropylsilyl chloride 
• 114566-88-0 1-triisopropylsilanyl-1H-imidazole 

Downstream Products

• 65-85-0 benzoic acid 
• 532-55-8 Benzoyl isothiocyanate 

Relevant articles and documents

Visible-Light-Induced in Situ Generation of Fischer-Type Copper Carbene Complexes from Acylsilanes and Its Application to Catalytic [4 + 1] Cycloaddition with Siloxydienes

A novel methodology for in situ generation of Fischer-type metal–carbene complexes was developed. Photoirradiation to a mixture of an acylsilane and a cationic copper complex cleanly gave a Fischer-type copper–siloxycarbene complex, which was detected by spectroscopic methods. This carbene complex reacted with siloxydienes in a [4 + 1] cycloaddition manner to give cyclopentene derivatives. It is noteworthy that this reaction proceeds with a catalytic amount of copper through in situ generation of a Fischer-type copper–siloxycarbene complex intermediate.

Triphenylphosphine-catalyzed dehydrogenative coupling reaction of carboxylic acids with silanes - A convenient method for the preparation of silyl esters

Triphenylphosphine has been found to be an efficient catalyst for the dehydrosilylation of carboxylic acids with silanes. In the presence of 4 mol % of triphenylphosphine (PPh3), dehydrosilylation reactions in DMF afforded the corresponding silyl esters at 120 °C in good yield.

Effective silylation of carboxylic acids under solvent-free conditions with tert-butyldimethylsilyl chloride (TBDMSCL) and triisopropylsilyl chloride (TIPSCL)

Varions types of carboxylic acids can be converted effectively to their corresponding TBDMS and TIPS esters using TBDMSCI and TIPSCI in the presence of imidazole under solvent-free conditions. The advantage of this modified method in comparison with that reported by Corey is the elimination of DMF, which eliminates aqueous work-up. The method is not a time-consuming process and the reactions proceed spontaneously. By this method, absolute chemoselectivity for the protection of carboxylic acid functions in the presence of 2°, 3° hydroxyl groups are observed.