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19777-66-3

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19777-66-3 Usage

Description

(S)-(-)-1,2-Diaminopropane dihydrochloride is an organic compound with the chemical formula C3H12N2·2HCl. It is a white solid and is known for its role in the synthesis of various pharmaceutical compounds and chiral imidazoline derivatives.

Uses

Used in Pharmaceutical Synthesis:
(S)-(-)-1,2-Diaminopropane dihydrochloride is used as a key intermediate in the synthesis of Dexrazoxane, a cardiac medicine. It plays a crucial role in the development of this medication, which is used to protect the heart from damage caused by certain cancer treatments.
Used in Chiral Imidazoline Derivatives:
(S)-(-)-1,2-Diaminopropane dihydrochloride is also used in the preparation of chiral imidazoline derivatives, which exhibit moderate α-adrenergic blocking activity. These derivatives have potential applications in the development of new medications for various medical conditions. Some examples of these derivatives include:
(S)-(-)-4-methyl-2-(1-naphthylmethyl)imidazoline hydrochloride
(S)-(-)-2-benzyl-4-methylimidazoline picrate
(S)-(-)-2-[(2,6-dichlorophenyl)imino]-4-methylimidazolidine hydrochloride

Check Digit Verification of cas no

The CAS Registry Mumber 19777-66-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,7,7 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 19777-66:
(7*1)+(6*9)+(5*7)+(4*7)+(3*7)+(2*6)+(1*6)=163
163 % 10 = 3
So 19777-66-3 is a valid CAS Registry Number.
InChI:InChI=1/C3H10N2.2ClH/c1-3(5)2-4;;/h3H,2,4-5H2,1H3;2*1H/t3-;;/m0../s1

19777-66-3 Well-known Company Product Price

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  • TCI America

  • (D2828)  (S)-1,2-Diaminopropane Dihydrochloride  >98.0%(T)

  • 19777-66-3

  • 1g

  • 790.00CNY

  • Detail
  • Aldrich

  • (412562)  (S)-(−)-1,2-Diaminopropanedihydrochloride  99%

  • 19777-66-3

  • 412562-1G

  • 1,022.58CNY

  • Detail

19777-66-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-propane-1,2-diamine,dihydrochloride

1.2 Other means of identification

Product number -
Other names (S)-(-)-Diaminopropane Hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19777-66-3 SDS

19777-66-3Relevant articles and documents

Schiff base complexes derived from salicylaldehyde with amine, [Ni(1,2-pn)2Cl2]·3H2O and [Cu(1,2-pn)2]SO4·2H2O, as complex ligands

Khalil, Saied M. E.,Stefan, Shaker L.,Bashir, Khaled A.

, p. 927 - 951 (2001)

-

Synthesis of a water-soluble chiral NMR shift reagent: (S)-PDTA

Florini, Nicola,Arnaud, Gaelle F.,Konya, Balint,Zucchi, Claudia,Palyi, Gyula

, p. 1036 - 1039 (2009)

A five-step synthesis of the water-soluble chiral polydentate ligand, (S)-PDTA [(S)-PDTA = N,N,N′,N′-tetrakis[(hydroxycarbonyl)methyl]-(S)-1,2-diaminopropane] starting from l-alanine has been worked out, via steps with retention of chirality. Total yield is 50.7% (average of ~88% for each step), while published methods report 33.4% total yield over four steps.

Synthesis, Characterization, and Optical Properties of New Organic–Inorganic Hybrid Perovskites [(NH3)2(CH2)3]CuCl4 and [(NH3)2(CH2)4]CuCl2Br

Abdel-Aal, Seham K.,Kandeel, Mohamed F.,El-Sherif, Ashraf F.,Abdel-Rahman, Ahmed S.

, (2021/05/03)

Organic–inorganic hybrid perovskites (OIHs) are exceptionally promising sector of novel materials for optoelectronic applications. Herein, the OIHs of the formula [(NH3)2(CH2)3]CuCl4 labeled by C

Simplified syntheses of the water-soluble chiral shift reagents Sm-(R)-pdta and Sm-(S)-pdta

Hrubá, Lucie,Budě?ínsky, Milo?,Pícha, Jan,Jirá?ek, Ji?í,Vaněk, Václav

supporting information, p. 6296 - 6297 (2013/11/06)

The chiral shift reagents Sm-(R)-pdta and Sm-(S)-pdta, which are based on (R)- or (S)-1,2-diaminopropane-N,N,N′,N′-tetraacetic acid were synthesized from easily accessible compounds in three simple steps, which makes the method suitable for laboratory-scale production. In addition, a new and efficient method for the preparation of pure anhydrous (R)- or (S)-1,2-diaminopropane-N,N,N′,N′-tetraacetic acid was developed.

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