197847-92-0 Usage
Description
(6-[3-(TRIFLUOROMETHOXY)PHENYL]PYRIDIN-3-YL)METHANOL is a chemical compound characterized by a molecular structure that features a pyridine ring connected to a phenyl ring, which is further adorned with a trifluoromethoxy group. (6-[3-(TRIFLUOROMETHOXY)PHENYL]PYRIDIN-3-YL)METHANOL also includes a methanol group attached to the pyridine ring. It is a white solid at room temperature and is widely utilized in the realm of chemical research and development. Its unique structural attributes and reactivity make it a promising candidate for applications in the pharmaceutical and agrochemical industries.
Uses
Used in Pharmaceutical Industry:
(6-[3-(TRIFLUOROMETHOXY)PHENYL]PYRIDIN-3-YL)METHANOL is used as a key intermediate in the synthesis of various drug candidates due to its structural characteristics and reactivity. Its potential applications in this field are currently under investigation, with ongoing research and studies aimed at exploring its properties and uses.
Used in Agrochemical Industry:
In the agrochemical sector, (6-[3-(TRIFLUOROMETHOXY)PHENYL]PYRIDIN-3-YL)METHANOL is employed as a building block for the development of novel pesticides. Its unique chemical structure and reactivity make it a valuable tool for scientists and researchers working on the creation of more effective and environmentally friendly pest control solutions.
Used in Chemical Research and Development:
(6-[3-(TRIFLUOROMETHOXY)PHENYL]PYRIDIN-3-YL)METHANOL serves as a valuable compound for scientists and researchers in the field of chemistry. It is commonly used in chemical research and development, where its structural properties and reactivity are harnessed to create new chemical entities and explore their potential applications across various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 197847-92-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,7,8,4 and 7 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 197847-92:
(8*1)+(7*9)+(6*7)+(5*8)+(4*4)+(3*7)+(2*9)+(1*2)=210
210 % 10 = 0
So 197847-92-0 is a valid CAS Registry Number.
197847-92-0Relevant articles and documents
Antitubercular and Antiparasitic 2-Nitroimidazopyrazinones with Improved Potency and Solubility
Ang, Chee Wei,Tan, Lendl,Sykes, Melissa L.,Abugharbiyeh, Neda,Debnath, Anjan,Reid, Janet C.,West, Nicholas P.,Avery, Vicky M.,Cooper, Matthew A.,Blaskovich, Mark A. T.
, p. 15726 - 15751 (2020/12/02)
Following the approval of delamanid and pretomanid as new drugs to treat drug-resistant tuberculosis, there is now a renewed interest in bicyclic nitroimidazole scaffolds as a source of therapeutics against infectious diseases. We recently described a nitroimidazopyrazinone bicyclic subclass with promising antitubercular and antiparasitic activity, prompting additional efforts to generate analogs with improved solubility and enhanced potency. The key pendant aryl substituent was modified by (i) introducing polar functionality to the methylene linker, (ii) replacing the terminal phenyl group with less lipophilic heterocycles, or (iii) generating extended biaryl side chains. Improved antitubercular and antitrypanosomal activity was observed with the biaryl side chains, with most analogs achieved 2- to 175-fold higher activity than the monoaryl parent compounds, with encouraging improvements in solubility when pyridyl groups were incorporated. This study has contributed to understanding the existing structure-activity relationship (SAR) of the nitroimidazopyrazinone scaffold against a panel of disease-causing organisms to support future lead optimization.
