19802-60-9

Basic information

• Product Name: 8-methoxy-6,11-dihydrothiochromeno[4,3-b]indole
• Synonyms: 6,11-Dihydro-8-methoxy-1-benzothiopyrano[4,3-b]indole; 8-Methoxy-6,11-dihydrothiochromeno[4,3-b]indole
• CAS NO: 19802-60-9
• Molecular Formula: C₁₆H₁₃NOS
• Molecular Weight: 267.3455
• Mol File: 19802-60-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 514.5°C at 760 mmHg
• Flash Point: 265°C
• Density: 1.323g/cm³
• Vapor Pressure: 3.47E-10mmHg at 25°C
• Refractive Index: 1.733
• CAS DataBase Reference: 8-methoxy-6,11-dihydrothiochromeno[4,3-b]indole(CAS DataBase Reference)
• NIST Chemistry Reference: 8-methoxy-6,11-dihydrothiochromeno[4,3-b]indole(19802-60-9)
• EPA Substance Registry System: 8-methoxy-6,11-dihydrothiochromeno[4,3-b]indole(19802-60-9)

Safety Data

• Hazardous Substances Data: 19802-60-9(Hazardous Substances Data)

Upstream product

• 13851-03-1 7-methoxy-2,3-dihydrobenzo[3',2':5,6]thiopyran-4(4H)-one 
• 3471-32-7 4-Methoxyphenylhydrazine 
• 3528-17-4 2,3-dihydro-4H-[1]benzothiopyran-4-one 
• 19501-58-7 4-methoxyphenylhydrazine hydrochloride 

Downstream Products

• 880553-41-3 6a-[4-(2-chloro-ethoxy)-benzyl]-8-methoxy-6,6a-dihydro-5-thia-11-aza-benzo[a]fluorene 
• 880553-40-2 11-[4-(2-chloro-ethoxy)-benzyl]-8-methoxy-6,11-dihydro-5-thia-11-aza-benzo[a]fluorene 

Relevant articles and documents

NOVEL TETRACYCLIC HETEROATOM CONTAINING DERIVATIVES USEFUL AS SEX STEROID HORMONE RECEPTOR MODULATORS

The present invention is directed to novel tetracyclic heteroatom containing derivatives, pharmaceutical compositions containing them, their use in the treatment of disorders mediated by one or more sex steroid hormone receptors and processes for their preparation.

Discovery of indole-containing tetracycles as a new scaffold for androgen receptor ligands

A novel series of tetracyclic indoles have been designed, synthesized and evaluated as androgen receptor (AR) ligands. Studies of structure-activity relationships (SARs) were investigated, which led to some compounds in this series as strong binders to an