1986-70-5

Basic information

• Product Name: calotropin
• Synonyms: calotropin;(2α,3β)-14-Hydroxy-19-oxo-3,2-[[(2S,3S,4S,6R)-tetrahydro-3,4-dihydroxy-6-methyl-2H-pyran-2,3-diyl]bis(oxy)]-5α,14β-card-20(22)-enolide
• CAS NO: 1986-70-5
• Molecular Formula: C₂₉H₄₀O₉
• Molecular Weight: 532.6225
• Mol File: 1986-70-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 223° (dec)
• Boiling Point: 733.5°Cat760mmHg
• Flash Point: 241.5°C
• Appearance: /
• Density: 1.403g/cm³
• Vapor Pressure: 7.8E-25mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: calotropin(CAS DataBase Reference)
• NIST Chemistry Reference: calotropin(1986-70-5)
• EPA Substance Registry System: calotropin(1986-70-5)

Safety Data

• RIDADR: 3172
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 1986-70-5(Hazardous Substances Data)

Usage

General Description

Calotropin is a toxic chemical found in the Calotropis procera plant, also known as the Apple of Sodom. It is a cardenolide, a type of organic compound that is toxic to both humans and animals. Calotropin acts as a cardiac glycoside, meaning it can disrupt the normal functioning of the heart. It inhibits the sodium-potassium ATPase pump in cell membranes, leading to an increase in intracellular sodium and calcium levels. This can result in arrhythmias, heart failure, and other cardiovascular problems. In traditional medicine, calotropin has been used as a remedy for various ailments, but due to its toxicity, it is not recommended for medicinal purposes. Overall, calotropin is a dangerous chemical with potential health risks.

InChI:InChI=1/C29H40O9/c1-15-9-23(31)29(34)25(36-15)37-21-11-17-3-4-20-19(27(17,14-30)12-22(21)38-29)5-7-26(2)18(6-8-28(20,26)33)16-10-24(32)35-13-16/h10,14-15,17-23,25,31,33-34H,3-9,11-13H2,1-2H3/t15-,17+,18-,19+,20-,21-,22-,23+,25+,26-,27-,28+,29+/m1/s1

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