198622-40-1

Basic information

• Product Name: (S)-2-Benzyl-2-benzyloxycarbonylamino-4-(tert-butoxycarbonylmethyl-amino)-butyric acid methyl ester
• Synonyms: (S)-2-Benzyl-2-benzyloxycarbonylamino-4-(tert-butoxycarbonylmethyl-amino)-butyric acid methyl ester
• CAS NO: 198622-40-1
• Molecular Weight: 470.566
• Mol File: 198622-40-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-Benzyl-2-benzyloxycarbonylamino-4-(tert-butoxycarbonylmethyl-amino)-butyric acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-Benzyl-2-benzyloxycarbonylamino-4-(tert-butoxycarbonylmethyl-amino)-butyric acid methyl ester(198622-40-1)
• EPA Substance Registry System: (S)-2-Benzyl-2-benzyloxycarbonylamino-4-(tert-butoxycarbonylmethyl-amino)-butyric acid methyl ester(198622-40-1)

Safety Data

• Hazardous Substances Data: 198622-40-1(Hazardous Substances Data)

Upstream product

• 198622-39-8 (R)-2-Benzyl-2-benzyloxycarbonylamino-pent-4-enoic acid methyl ester 
• 2448-45-5 Cbz-D-Phe 
• 27532-96-3 glycine tert-butyl ester hydrochloride 

Downstream Products

• 198622-42-3 C₂₉H₃₇N₇O₇ 
• 198622-41-2 ((S)-3-Benzyl-3-benzyloxycarbonylamino-2-oxo-pyrrolidin-1-yl)-acetic acid tert-butyl ester 

Relevant articles and documents

Rational design and synthesis of a novel, selective class of thrombin inhibitors: P1-argininal derivatives incorporating P3-P4 quaternary lactam dipeptide surrogates

SAR and molecular modeling investigations on the potent and selective thrombin inhibitor 1b (CVS 1578) and related serine protease inhibitors led to the design of series 2a-g, featuring quaternary α-amino-α-benzyl-lactam scaffolds that serve as novel P3-P4 dipeptide mimics. The design, synthesis, and biological activity of these targets an presented.