19869-61-5

Basic information

• Product Name: 2-(2-chloro-acetylamino)-4-phenyl-thiazole-5-carboxylic acid ethyl ester
• CAS NO: 19869-61-5
• Molecular Weight: 324.788
• Mol File: 19869-61-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-chloro-acetylamino)-4-phenyl-thiazole-5-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-chloro-acetylamino)-4-phenyl-thiazole-5-carboxylic acid ethyl ester(19869-61-5)
• EPA Substance Registry System: 2-(2-chloro-acetylamino)-4-phenyl-thiazole-5-carboxylic acid ethyl ester(19869-61-5)

Safety Data

• Hazardous Substances Data: 19869-61-5(Hazardous Substances Data)

Upstream product

• 64399-23-1 ethyl 4-phenyl-2-aminothiazole-5-carboxylate 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 36793-55-2 2-[2-(4-benzoylamino-piperidin-1-yl)-acetylamino]-4-phenyl-thiazole-5-carboxylic acid ethyl ester 

Relevant articles and documents

Synthesis and antimicrobial evaluation of novel ethyl 2-(2-(4-substituted)acetamido)-4-subtituted-thiazole-5-carboxylate derivatives

A series of novel molecules containing thiazole ring structure were designed and synthesized. The structures of the synthesized compounds were elucidated and confirmed by1H NMR,13C NMR, Mass spectrum and the purity was checked through HPLC analysis. Among these synthesized compounds, 3a–3i and 6a–6c were tested for their antimicrobial activity (minimum inhibitory concentration) against a series of strains of Bacillus subtilis, Staphylococcus aureus and Escherichia coli for antibacterial activity and against the strains of Candida albicans, Aspergillus flavus and Aspergillus niger for antifungal activity respectively. The results of the antimicrobial screening data revealed that most of the tested compounds showed moderate to good microbial inhibitions.