19878-11-6

Basic information

• Product Name: (9Z,12Z)-N-(4-ethoxyphenyl)linoleamide
• Synonyms: (9Z,12Z)-N-(4-ethoxyphenyl)linoleamide
• CAS NO: 19878-11-6
• Molecular Weight: 399.617
• Mol File: 19878-11-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (9Z,12Z)-N-(4-ethoxyphenyl)linoleamide(CAS DataBase Reference)
• NIST Chemistry Reference: (9Z,12Z)-N-(4-ethoxyphenyl)linoleamide(19878-11-6)
• EPA Substance Registry System: (9Z,12Z)-N-(4-ethoxyphenyl)linoleamide(19878-11-6)

Safety Data

• Hazardous Substances Data: 19878-11-6(Hazardous Substances Data)

Upstream product

• 77379-13-6 C₂₁H₃₆O₄ 
• 156-43-4 4-Ethoxyaniline 
• 60-33-3 linoleic acid 

Relevant articles and documents

Synthesis of Acetaminophen Analogues Containing α-Amino Acids and Fatty Acids for Inhibiting Hepatotoxicity

Acetaminophen is a popular antipyretic analgesic medicine that has weaker anti-inflammatory properties and lower incidence of side effects than nonsteroidal anti-inflammatory drugs (NSAIDs). However, acetaminophen causes hepatotoxicity due to the reactive metabolite N -acetyl- p -benzoquinone imine (NAPQI). We have obtained acetaminophen analogues in 57-99percent yields by using aniline derivatives with protected α-amino acids and fatty acids via the corresponding mixed carbonic carboxylic anhydrides in aqueous MeCN. We have also succeeded in synthesizing AM404 analogues in 76-97percent yields, which are expected to be promising candidates for reducing hepatotoxicity.