198954-96-0

Basic information

• Product Name: N,N-Bis-cyanomethyl-4-methyl-benzenesulfonamide
• CAS NO: 198954-96-0
• Molecular Weight: 249.293
• Mol File: 198954-96-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N-Bis-cyanomethyl-4-methyl-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Bis-cyanomethyl-4-methyl-benzenesulfonamide(198954-96-0)
• EPA Substance Registry System: N,N-Bis-cyanomethyl-4-methyl-benzenesulfonamide(198954-96-0)

Safety Data

• Hazardous Substances Data: 198954-96-0(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 628-87-5 iminodiacetonitrile 

Downstream Products

• 1027162-60-2 6,20-Bis-(toluene-4-sulfonyl)-3,6,9,17,20,23-hexaaza-tricyclo[23.3.1.1^11,15]triaconta-1⁽²⁸⁾,11,13,15⁽³⁰⁾,25⁽²⁹⁾,26-hexaene-3,9,17,23-tetracarbonitrile 
• 198954-99-3 3,9,17,23-Tetramethyl-6,20-bis-(toluene-4-sulfonyl)-3,6,9,17,20,23-hexaaza-tricyclo[23.3.1.1^11,15]triaconta-1⁽²⁸⁾,11,13,15⁽³⁰⁾,25⁽²⁹⁾,26-hexaene 
• 23539-15-3 N,N-bis(2-aminoethyl)-4-methyl-benzenesulfonamide 

Relevant articles and documents

Supramolecular catalysis of H/D exchange in pyruvate by macrocyclic polyamines involving a reactive iminium intermediate

The activity of a series of macrocyclic polyamines as catalysts for proton exchange has been investigated. Structural and physico-chemical studies demonstrate the ability of these receptors to recognize pyruvate, form a covalent iminium intermediate and catalyse H/D exchange at the CH3 position. The reaction follows Michaelis-Menten kinetics with a rate enhancement higher than 4.8 × 105 (kcat/kuncat). The process also represents a potential entry into the catalysis of aldol condensation reactions.