19909-85-4

Basic information

• Product Name: 1-(Dichlorophosphino)-4-methoxybenzene
• Synonyms: (p-Methoxyphenyl)dichlorophosphine;1-(Dichlorophosphino)-4-methoxybenzene;4-Methoxyphenyldichlorophosphine
• CAS NO: 19909-85-4
• Molecular Formula: C₇H₇Cl₂OP
• Molecular Weight: 209.01
• Mol File: 19909-85-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(Dichlorophosphino)-4-methoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Dichlorophosphino)-4-methoxybenzene(19909-85-4)
• EPA Substance Registry System: 1-(Dichlorophosphino)-4-methoxybenzene(19909-85-4)

Safety Data

• Hazardous Substances Data: 19909-85-4(Hazardous Substances Data)

Usage

Type of compound

Substituted phosphine ligand

Application

Organometallic and coordination chemistry

Function

Binds to metal ions to form stable complexes

Structure

Benzene ring with a methoxy group and two chlorine atoms attached to a phosphorus atom

Versatility

Useful in chemical synthesis and catalysis

Industrial uses

Production of pharmaceuticals, agrochemicals, and other applications

Coordination ability

Strong

Stability

High

Importance

Building block for various chemical reactions and processes

Upstream product

• 2097-72-5 bis(p-anisyl)mercury 
• 100-66-3 methoxybenzene 
• 93296-09-4 4-methoxyphenylzinc chloride 

Downstream Products

• 92789-73-6 di(n-butyl)(p-methoxyphenyl)phosphine 
• 1056473-75-6 N,N'-dibenzyl-N,N'-dimethyl-P-(4-methoxyphenyl)phosphonic diamide 
• 16513-36-3 pentakis(-methoxyphenyl)cyclopentaphosphine 
• 1122103-05-2 diphenyl 4-methoxyphenylphosphonite 
• 97913-32-1 (dichloro-(p-methoxyphenyl)-phosphane)tetracarbonyliron 
• 95608-79-0 (C₆H₄(OCH₃))Cl₂PMn(C₅H₅)(CO)2 

Relevant articles and documents

The Formation of P-C Bonds Utilizing Organozinc Reagents for the Synthesis of Aryl- A nd Heteroaryl-Dichlorophosphines

Aryl- A nd heteroaryl-dichlorophosphines are mildly and selectively made in a one-pot synthesis in moderate to good yields starting from the respective aryl bromides or five-membered heterocycles, following lithiation with nBuLi, transmetalation with ZnCl

A direct and new convenient oxidation: Synthesis of substituted arylphosphonates from aromatics

An easy synthesis of aryl phosphonates by oxidation from aryldichlorophosphines with iodine in good yields is described. Aryldichlorophosphines are obtained by reaction of phosphorous trichloride with some aromatics in presence of various Lewis acids. BiCl3 and Bi(OTf)3 are used for the first time and bismuth trichloride is, for the first time in the case of anisole or thioanisole phosphonylation, used as a true regenerable Lewis acid catalyst in a reaction of direct phosphonylation of aromatics.

SYNTHESIS OF PHOSPHONIC DICHLORIDES AND CORRELATION OF THEIR P-31 CHEMICAL SHIFTS

Various mono-substituted diethyl arylphosphonates were prepared in good yield by treatment of aryl bromides or iodides with triethyl phosphite in the presence of NiCl2 or alternatively, addition of the aryl grignard reagent to diethyl phosphorochloridate.