199170-74-6Relevant articles and documents
Addition of nucleophiles to 6-vinylpurines
veras, Anniken T.,Bakkestuen, Anne Kristin,Gundersen, Lise-Lotte,Rise, Frode
, p. 1116 - 1124 (2007/10/03)
6-Vinylpurines readily participate in nucleophilic addition reactions. Treatment with sodium salts of alcohols and thiols, as well as stabilised carbanions, results in clean conversion into a variety of functionalized purine derivatives. Additions performed in the presence of acid give 1:1 adducts together with dimeric purine products. Under acidic conditions the adduct first formed reacts further with another molecule of vinylpurine. Acta Chemica Scandinavica 1997.