199188-29-9 Usage
Description
2-(TRIFLUOROMETHYL)PHENYL TRIFLUOROMETHANESULFONATE, also known as trifluoromethanesulfonic acid, is an organic compound characterized by its trifluoromethyl and trifluoromethylsulfonyl functional groups. It is a potent reagent in organic synthesis and possesses unique chemical properties that make it suitable for various applications.
Uses
Used in Green Synthetic Preparation:
2-(TRIFLUOROMETHYL)PHENYL TRIFLUOROMETHANESULFONATE is used as a reagent in the green synthetic preparation of N-aryl sulfonamides. It facilitates the reaction under mild conditions, which is beneficial for the environment and the overall sustainability of the process.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(TRIFLUOROMETHYL)PHENYL TRIFLUOROMETHANESULFONATE is used as a key intermediate in the synthesis of various drugs, particularly those with anti-inflammatory, analgesic, and antipyretic properties. Its unique reactivity allows for the efficient production of these therapeutic compounds.
Used in Chemical Research:
2-(TRIFLUOROMETHYL)PHENYL TRIFLUOROMETHANESULFONATE is also utilized in chemical research as a versatile reagent for the functionalization of various organic substrates. Its ability to participate in a wide range of reactions, such as substitution, addition, and elimination, makes it a valuable tool for the development of new chemical entities and materials.
Used in Material Science:
In the field of material science, 2-(TRIFLUOROMETHYL)PHENYL TRIFLUOROMETHANESULFONATE is employed in the synthesis of novel polymers and materials with specific properties, such as enhanced thermal stability, chemical resistance, and mechanical strength. Its unique structure contributes to the development of advanced materials for various applications, including aerospace, electronics, and automotive industries.
Overall, 2-(TRIFLUOROMETHYL)PHENYL TRIFLUOROMETHANESULFONATE is a versatile and valuable compound with a wide range of applications across different industries, including pharmaceuticals, green synthetic chemistry, chemical research, and material science. Its unique properties and reactivity make it an essential component in the development of new drugs, materials, and processes.
Check Digit Verification of cas no
The CAS Registry Mumber 199188-29-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,9,1,8 and 8 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 199188-29:
(8*1)+(7*9)+(6*9)+(5*1)+(4*8)+(3*8)+(2*2)+(1*9)=199
199 % 10 = 9
So 199188-29-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H4F6O3S/c9-7(10,11)5-3-1-2-4-6(5)17-18(15,16)8(12,13)14/h1-4H
199188-29-9Relevant articles and documents
Suzuki-miyaura cross-coupling reactions in flow: Multistep synthesis enabled by a microfluidic extraction
Noal, Timothy,Kuhn, Simon,Musacchio, Andrew J.,Jensen, Klavs F.,Buchwald, Stephen L.
supporting information; experimental part, p. 5943 - 5946 (2011/08/02)
Continuous success: A continuous-flow Suzuki-Miyaura cross-coupling reaction starting from phenols was made possible through use of an efficient microfluidic extraction operation and a packed-bed reactor. Various biaryls were obtained in excellent yield (
On the preparation of ortho-trifluoromethyl phenyl triflate
Gill, Duncan,Hester, Alison J.,Lloyd-Jones, Guy C.
, p. 2547 - 2548 (2007/10/03)
In contrast to an earlier report advocating a copper-mediated trifluoromethylation of ortho-iodophenyl triflate, ortho-trifluoromethyl phenyl triflate may be prepared simply by reacting the corresponding phenol with triflic anhydride in the presence of a
