199275-18-8

Basic information

• Product Name: 1-(3-phenylpropyl)-1-(1,1-dimethylethyl) ether
• Synonyms: 1-(3-phenylpropyl)-1-(1,1-dimethylethyl) ether
• CAS NO: 199275-18-8
• Molecular Weight: 192.301
• Mol File: 199275-18-8.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 1-(3-phenylpropyl)-1-(1,1-dimethylethyl) ether(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-phenylpropyl)-1-(1,1-dimethylethyl) ether(199275-18-8)
• EPA Substance Registry System: 1-(3-phenylpropyl)-1-(1,1-dimethylethyl) ether(199275-18-8)

Safety Data

• Hazardous Substances Data: 199275-18-8(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 13058-24-7 tert-butoxytrimethylsilane 
• 122-97-4 3-Phenyl-1-propanol 
• 115-11-7 isobutene 
• 75-65-0 tert-butyl alcohol 
• 501-52-0 3-Phenylpropionic acid 
• 16537-10-3 tert-butyl 3-phenylpropanoate 
• 257956-68-6 1-(1,1-dimethylethoxy)-3-phenylpropyl acetate 
• 873-49-4 cyclopropylbenzene 
• 623-26-7 terephthalonitrile 
• 873-49-4 phenylcyclopropane cation radical 

Downstream Products

• 122-97-4 3-Phenyl-1-propanol 

Relevant articles and documents

Hydrosilane-Promoted Facile Deprotection of tert-Butyl Groups in Esters, Ethers, Carbonates, and Carbamates

Combination of PdCl2 with 1,1,3,3-tetramethyldisiloxane in the presence of activated carbon was found to be an effective catalyst system for the cleavage reaction of C?O bond of O?t-Bu moieties. The present catalytic reaction offers a practical method for the deprotection of tert-butyl esters, tert-butyl ethers, O-Boc, and N-Boc derivatives under mild conditions. The addition of activated carbon in the reaction mixture was proved to be crucial for not only sustaining the catalytic activity but also trapping the palladium species after the reaction. (Figure presented.).

An efficient method for the reductive conversion of acyclic esters to ethers via a TMS-protected acetal

We report an efficient two step process for the reduction of non-aromatic esters to the corresponding ethers via the intermediate TMS-protected acetal. The acetal formed after the first step can be carried on directly to the subsequent reduction to the ether without purification. The ester reduction step was monitored using in-situ ReactIR for disappearance of the C[dbnd]O peak, allowing for the exact determination of time and equivalents of the reducing agent. Furthermore, use of TMS-imidazole to form the acetal has allowed us to dramatically reduce the overall reaction time required for the two step procedure.

HYDROXY GROUP PROTECTING AGENT AND HYDROXY GROUP PROTECTION METHOD

To provide: a hydroxy group protecting agent which is stable and easy to use, does not have carcinogenicity, a tearing property or the like, and is inexpensive; and a hydroxy group protection method which enables the protection of a hydroxy group under acidic conditions. [Solution] A hydroxy group protecting agent in which at least one protecting group is bound to a nitrogen-containing electron-withdrawing heterocyclic ring through any one of an oxygen atom, a sulfur atom and a nitrogen atom. The heterocyclic ring is a triazine ring or the like, and the protecting group is a benzyl group or the like. Specifically, the hydroxy group protecting agent is 2,4,6-tribenzyloxy-1,3,5-triazine, 2,4,6-tris(4-methoxybenzyloxy)-1,3,5-triazine or the like. In addition, 2,4,6-tris(t-butoxy)-1,3,5-triazine or the like can also be used. For protecting a hydroxy group, a compound of interest which has a hydroxy group is reacted with the hydroxy group protecting agent under acidic conditions.