1993-77-7 Usage
Description
1-cyclopropyl-2,2,2-trifluoroethan-1-ol is a chemical compound with the molecular formula C5H7F3O. It features a cyclopropyl group, a trifluoromethyl group, and a hydroxyl group attached to the central carbon atom, which imparts unique chemical properties. The presence of the trifluoroethan-1-ol group also endows it with high electronegativity and lipophilicity, making it a versatile compound for various chemical reactions.
Uses
Used in Pharmaceutical Industry:
1-cyclopropyl-2,2,2-trifluoroethan-1-ol is used as an intermediate in the synthesis of pharmaceuticals. Its unique chemical properties and high electronegativity make it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
1-cyclopropyl-2,2,2-trifluoroethan-1-ol is also utilized as an intermediate in the synthesis of agrochemicals. Its lipophilicity and reactivity contribute to the creation of effective compounds for agricultural applications.
Used in Organic Compound Production:
1-cyclopropyl-2,2,2-trifluoroethan-1-ol serves as a building block in the production of various organic compounds. Its distinct structure and properties allow for the synthesis of a wide range of chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 1993-77-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,9 and 3 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1993-77:
(6*1)+(5*9)+(4*9)+(3*3)+(2*7)+(1*7)=117
117 % 10 = 7
So 1993-77-7 is a valid CAS Registry Number.
1993-77-7Relevant articles and documents
ION CHANNEL MODULATORS
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Paragraph 0349; 0350, (2021/06/11)
The present invention is directed to, in part, fused heteroaryl compounds and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including neurological disorders (e.g., Dravet syndrome, epilepsy), pain, and neuromuscular disorders are also provided herein.
Electron-Donating Ability of the Cyclopropyl Substituent in the Solvolyses of an α-CF3-Substituted Secondary-Alkyl Tosylate
Roberts, Donald D.
, p. 5661 - 5665 (2007/10/02)
The solvolysis rates of cyclopropyl(trifluoromethyl)carbinyl tosylate (1) have been determined in a series of aqueous alcohol, aqueous trifluoroethanol, and carboxylic acid solvents.Analysis of the rate data for percent internal-return isomerization and salt effects and correlation with YOTs values indicates that 1 underwent solvolysis by the kΔ pathway.Comparison of the relative ability of cyclopropyl and phenyl groups to stabilize carbocation-like transition states in solvolysis reactions of the secondary systems RCH(Y)CH3 and RCH(Y)CF3 reveals that replacement of phenyl with cyclopropyl increases the rate in both systems by a factor of 102.