199609-35-3Relevant articles and documents
Fibrinogen receptor (GPIIb-IIIa) antagonists derived from 5,6-bicyclic templates. Amidinoindoles, amidinoindazoles, and amidinobenzofurans containing the N-α-sulfonamide carboxylic acid function as potent platelet aggregation inhibitors
Su, Ting,Naughton, Mary Ann H.,Smyth, Mark S.,Rose, Jack W.,Arfsten, Ann E.,McCowan, Jefferson R.,Jakubowski, Joseph A.,Wyss, Virginia L.,Ruterbories, Kenneth J.,Sall, Daniel J.,Scarborough, Robert M.
, p. 4308 - 4318 (2007/10/03)
A series of highly potent and specific fibrinogen receptor antagonists have been discovered and optimized through structural modification of the novel amidinoindole and benzofuran compounds, I and II. Systematic linker optimization afforded the amidinoben
