199729-94-7

Basic information

• Product Name: C₁₇H₂₄N₆O₈
• CAS NO: 199729-94-7
• Molecular Weight: 440.413
• Mol File: 199729-94-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₂₄N₆O₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₂₄N₆O₈(199729-94-7)
• EPA Substance Registry System: C₁₇H₂₄N₆O₈(199729-94-7)

Safety Data

• Hazardous Substances Data: 199729-94-7(Hazardous Substances Data)

Relevant articles and documents

Stigonemapeptin, an Ahp-containing depsipeptide with elastase inhibitory activity from the bloom-forming freshwater cyanobacterium Stigonema sp.

Stigonemapeptin (1), a depsipeptide containing an Ahp (3-amino-6-hydroxy-2- piperidone) residue, was isolated from a bloom sample of the freshwater cyanobacterium Stigonema sp. collected from North Nokomis Lake in the Highland Lake District of northern Wisconsin. The planar structure was determined by 1D and 2D NMR experiments as well as HRESIMS analysis. The absolute configurations of the amino acids were determined using the advanced Marfey's method after acid hydrolysis. Stigonemapeptin (1), characterized by the presence of the Ahp residue, also contained the modified amino acids Abu (2-amino-2-butenoic acid) and N-formylated Pro. Stigonemapeptin (1) showed in vitro elastase and chymotrypsin inhibitory activity, with IC50 values of 0.26 and 2.93 μM, respectively.