199786-58-8

Basic information

• Product Name: 5-BROMO-2-IODOBENZENEMETHANOL
• Synonyms: 5-BROMO-2-IODOBENZENEMETHANOL;5-BROMO-2-IODOBENZYL ALCOHOL
• CAS NO: 199786-58-8
• Molecular Formula: C₇H₆BrIO
• Molecular Weight: 312.94
• Mol File: 199786-58-8.mol
• Article Data: 29

Chemical Properties

• Melting Point: 114-155 °C
• Boiling Point: 346.3±27.0 °C(Predicted)
• Appearance: /
• Density: 2.211±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 13.93±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-2-IODOBENZENEMETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-IODOBENZENEMETHANOL(199786-58-8)
• EPA Substance Registry System: 5-BROMO-2-IODOBENZENEMETHANOL(199786-58-8)

Safety Data

• Hazardous Substances Data: 199786-58-8(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-iodobenzenemethanol is a chemical compound with the molecular formula C7H6BrIO. It is a white to off-white solid that is used in various chemical and pharmaceutical applications. The compound is a derivative of benzene and contains both bromine and iodine atoms. It is commonly used as a building block in the synthesis of other organic compounds and as a reagent in chemical reactions. 5-Bromo-2-iodobenzenemethanol has potential applications in the pharmaceutical industry for the development of new drugs and in the production of specialty chemicals. It is important to handle and store this compound carefully, as it is potentially hazardous and can cause skin and eye irritation.

Upstream product

• 88-67-5 2-Iodobenzoic acid 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 495414-06-7 4-bromo-2-(bromomethyl)-1-iodobenzene 
• 116632-39-4 2-methyl-4-bromoiodobenzene 
• 118-92-3 anthranilic acid 
• 181765-86-6 5-bromo-2-iodo-benzoic acid methyl ester 
• 5794-88-7 5-Bromo-2-aminobenzoic acid 
• 21740-00-1 5-bromo-2-iodo-benzoic acid 

Downstream Products

• 689291-89-2 5-bromo-2-iodobenzaldehyde 
• 1067882-41-0 ((5-bromo-2-iodobenzyl)oxy)(tert-butyl)dimethylsilane 
• 885693-79-8 2,5-bis((trimethylsilyl)ethynyl)benzaldehyde 
• 1038395-11-7 5-bromo-2-((triisopropylsilyl)ethynyl)benzaldehyde 
• 1038395-08-2 1,4-bis(5-bromo-2-iodostyryl)benzene 
• 1038395-09-3 C₄₂H₅₀Si₄ 
• 1038395-10-6 C₃₀H₁₈ 
• 1038395-15-1 C₆₂H₄₂O₈ 
• 1263055-18-0 2,5-diethynylbenzaldehyde 
• 1263055-20-4 C₂₇H₁₈O₅ 
• 1263055-24-8 2-((triisopropylsilyl)ethynyl)-5-((trimethylsilyl)ethynyl)benzaldehyde 
• 1263055-26-0 5-ethynyl-2-((triisopropylsilyl)ethynyl)benzaldehyde 
• 1263055-28-2 methyl 2-((3-formyl-4-((triisopropylsilyl)ethynyl)phenyl)ethynyl)benzoate 
• 1263055-30-6 methyl 2-((4-ethynyl-3-formylphenyl)ethynyl)benzoate 

Relevant articles and documents

A new solvatochromic linear π-conjugated dye based on phenylene-(poly)ethynylene as supersensitive low-level water detector in organic solvents

A novel class of phenylene-(poly)ethynylene-based dye Sensor 1 with remarkable properties of solvatochromism has been designed and synthesized. A long, coplanar and asymmetry electron-rich π-conjugated structure endows Sensor 1 with maximum solvatochromic

Pd(II)-Catalyzed Synthesis of Benzocyclobutenes by β-Methylene-Selective C(sp3)-H Arylation with a Transient Directing Group

Methylene-selective C-H functionalization is a significant hurdle that remains to be addressed in the field of Pd(II) catalysis. We report a Pd(II)-catalyzed synthesis of benzocyclobutenes by methylene-selective C(sp3)-H arylation of ketones. The reaction utilizes glycine as a transient directing group and a 2-pyridone ligand, which may govern the methylene selectivity by making intimate molecular associations with the substrate during concerted metalation-deprotonation. This reaction is shown to be highly selective for intramolecular methylene C(sp3)-H arylation, thus enabling sequential C(sp3)-H functionalization.

Iodolopyrazolium Salts: Synthesis, Derivatizations, and Applications

The synthesis of iodolopyrazolium triflates via an oxidative cyclization of 3-(2-iodophenyl)-1H-pyrazoles is described. The reaction is characterized by a broad substrate scope, and various applications of these novel cyclic iodolium salts acting as useful synthetic intermediates are demonstrated, in particular in site-selective ring openings. This was finally applied to generate derivatives of the anti-inflammatory drug celecoxib. Their application as highly active halogen-bond donors is shown as well.