199792-79-5Relevant articles and documents
An inverse approach in oligodeoxyribonucleotide synthesis
Wagner, Thomas,Pfleiderer, Wolfgang
, p. 1657 - 1660 (1997)
We synthesized 3'-O-dimetboxytrityl-5'O-phosphoramidites and 5'-O- succinates which can be used as monomeric building blocks for the built up of oligodeoxyribonucleotides in the alternative 5'-3' direction. With this inverse strategy oligonucleotide 3'-conjugates as well as 3'-3' and 5'-5' internucleotidic linkages can be easily formed.