2001-28-7

Basic information

• Product Name: 4'-METHYL-2-PHENYLACETOPHENONE
• Synonyms: NSC 20572;4'-METHYL-2-PHENYLACETOPHENONE;4-METHYLDEOXYBENZOIN;4-METHYLPHENYLBENZYL KETONE;BENZYL 4-METHYLPHENYL KETONE;BENZYL P-TOLUYLKETONE;DEOXY-4-METHYLBENZOIN;Benzyl 4-methylphenyl ketone, 1-(4-Methylphenyl)-2-phenylethan-1-one
• CAS NO: 2001-28-7
• Molecular Formula: C₁₅H₁₄O
• Molecular Weight: 210.27
• Product Categories: Aromatic Ketones (substituted);Aromatics
• Mol File: 2001-28-7.mol
• Article Data: 117

Chemical Properties

• Melting Point: 108-110°C
• Boiling Point: 343 °C at 760 mmHg
• Flash Point: 147.7 °C
• Appearance: /
• Density: 1.062 g/cm³
• Vapor Pressure: 7.25E-05mmHg at 25°C
• Refractive Index: 1.576
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 4'-METHYL-2-PHENYLACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-METHYL-2-PHENYLACETOPHENONE(2001-28-7)
• EPA Substance Registry System: 4'-METHYL-2-PHENYLACETOPHENONE(2001-28-7)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 2001-28-7(Hazardous Substances Data)

Usage

Chemical Properties

Pink Solid

InChI:InChI=1/C15H14O/c1-12-7-9-14(10-8-12)15(16)11-13-5-3-2-4-6-13/h2-10H,11H2,1H3

Upstream product

• 623-11-0 1-methyl-4-nitrosobenzene 
• 102-04-5 1,3-Diphenylpropanone 
• 26067-92-5 2-amino-1-phenyl-1-p-tolyl-ethanol 
• 64-19-7 acetic acid 
• 108-86-1 bromobenzene 
• 122-00-9 para-methylacetophenone 
• 6921-34-2 benzylmagnesium chloride 
• 104-87-0 4-methyl-benzaldehyde 
• 27992-27-4 sodium 2-benzylidene-1-tosylhydrazin-1-ide 
• 7664-93-9 sulfuric acid 
• 7647-01-0 hydrogenchloride 
• 2613-89-0 phenylmalonic acid 
• 108-88-3 toluene 
• 2417-95-0 p-tolyllithium 

Downstream Products

• 101109-89-1 3-oxo-2-phenyl-3-(4-methylphenyl)propanal 
• 193144-67-1 2-phenyl-1-p-tolyl-propenone 
• 4714-21-0 E-1-methyl-4-styryl-benzene 
• 2431-00-7 p-methylbenzil 
• 20498-63-9 1-(4-methylphenyl)-2-phenylethanol 
• 14310-20-4 4-methylbibenzyl 
• 14161-82-1 rac-1-(4-methylphenyl)-2-phenylpropan-1-one 
• 55810-37-2 2,3-diphenyl-1-p-tolyl-propan-1-one 
• 349082-24-2 (Z)-1-(1-chloro-2-phenylvinyl)-4-methylbenzene 
• 101089-41-2 (Z)-2-phenyl-1-(p-tolyl)ethan-1-one oxime 
• 860742-09-2 α,α-dibromo-4-methyl-deoxybenzoin 
• 67946-07-0 (Z)-(2-vinyloct-1-en-3-(p-tolyl)-1-yl)benzene 
• 2431-23-4 4-methylbenzoin 
• 71472-48-5 3-phenyl-4-p-tolyl-[1,2,5]thiadiazole 

Relevant articles and documents

MAGNETIC AND MICELLAR EFFECTS IN PHOTOREACTIONS. (13)C NMR DETERMINATION OF SELECTIVE (13)C ENRICHMENT IN A DIBENZYL KETONE PHOTOPRODUCT.

The photolysis of dibenzyl ketone (DBK) in micellar solution results in formation of 1-phenyl-4-methyl acetophenone (PMAP) as a minor product; quantitative integration of the (13)C NMR spectrum of PMAP produced by photolysis of DBK in micellar solution de

High-throughput photocapture approach for reaction discovery

Modern organic reaction discovery and development relies on the rapid assessment of large arrays of hypothesis-driven experiments. The time-intensive nature of reaction analysis presents the greatest practical barrier for the execution of this iterative process that underpins the development of new bioactive agents. Toward addressing this critical bottleneck, we report herein a high-throughput analysis (HTA) method of reaction mixtures by photocapture on a 384-spot diazirine-terminated self-assembled monolayer, and selfassembled monolayers for matrix-assisted laser desorption/ionization mass spectrometry (SAMDI-MS) analysis. This analytical platform has been applied to the identification of a single-electron-promoted reductive coupling of acyl azolium species.

Aerobic oxygenation of α-methylene ketones under visible-light catalysed by a CeNi3complex with a macrocyclic tris(salen)-ligand

A hetero-tetranuclear CeNi3 complex with a macrocyclic ligand catalysed the aerobic oxygenation of a methylene group adjacent to a carbonyl group under visible-light radiation to produce the corresponding α-diketones. The visible-light induced homolysis of the Ce-O bond of a bis(enolate) intermediate is proposed prior to aerobic oxygenation.

Visible-Light-Promoted [3 + 2] Cycloaddition of 2H-Azirines with Quinones: Access to Substituted Benzo[f]isoindole-4,9-diones

A visible-light-promoteded [3 + 2] cycloaddition reaction of 2H-azirines with quinones has been developed under mild reaction conditions. The reaction provides a general and efficient strategy for the synthesis of the benzo[f]isoindole-4,9-diones scaffold