201140-18-3Relevant articles and documents
In vitro photodynamic activity of lipid vesicles with zinc phthalocyanine derivative against Enterococcus faecalis
Sobotta, Lukasz,Dlugaszewska, Jolanta,Kasprzycki, Piotr,Lijewski, Sebastian,Teubert, Anna,Mielcarek, Jadwiga,Gdaniec, Maria,Goslinski, Tomasz,Fita, Piotr,Tykarska, Ewa
, p. 111 - 118 (2018)
Zinc(II) phthalocyanine bearing eight non-peripheral 2-propoxy substituents was subjected to physicochemical study and, after incorporation in lipid vesicles, assessed as a potential photosensitizer for antibacterial photodynamic therapy. The phthalocyani
A facile and regioselective synthesis of trans-heterofunctionalized porphyrazine derivatives
Forsyth, Timothy P.,Bradley G Williams,Montalban, Antonio Garrido,Stern, Charlotte L.,Barrett, Anthony G. M.,Hoffman, Brian M.
, p. 331 - 336 (2007/10/03)
New methodology was developed for the selective synthesis of regiochemically defined porphyrazines of the form M[pz(A2;B2)] (shown in Chart 1) where A and B represent peripheral functionalization attached to the β-positions of the pyrroles. Specifically, phthalonitriles or derivatives thereof with sterically bulky groups in positions 3 and 6, in particular 4,7- bis(isopropyloxy)-1,3-diiminoisoindoline (3) act as a 'trans director' when macrocyclized with heteroatom-appended maleonitriles under Linstead conditions, the result being preferential formation of the trans- M[pz(A2;B2)] pigment where A = SR, NMe2, OR, as well as R (shown in Chart 2). Linstead crossover macrocyclization of 3 with 4, 11, 15, and 18 gave pigments 10, 14, 17, and 19, respectively. These pigments were characterized by 1H NMR, 13C NMR, UV-visible spectroscopy, mass spectrometry, microanalysis, and 17 was characterized by single-crystal X-ray analysis.
