201162-53-0 Usage
Description
Tert-butyl 3,8-diazabicyclo[3.2.1]octane-3-carboxylate is an organic compound with a unique bicyclic structure. It is characterized by its ability to form stable complexes with various molecules, making it a versatile building block in organic synthesis and a potential candidate for pharmaceutical applications.
Uses
Used in Pharmaceutical Industry:
Tert-butyl 3,8-diazabicyclo[3.2.1]octane-3-carboxylate is used as a synthetic intermediate for the preparation of substituted pyrrolo[2,3-b]pyridines. These compounds are known to suppress toxic endoplasmic reticulum stress, which is a significant factor in the development of various diseases, including neurodegenerative disorders and certain types of cancer. By incorporating this compound into the synthesis of pyrrolo[2,3-b]pyridines, researchers can potentially develop novel therapeutic agents to target and alleviate endoplasmic reticulum stress-related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 201162-53-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,1,6 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 201162-53:
(8*2)+(7*0)+(6*1)+(5*1)+(4*6)+(3*2)+(2*5)+(1*3)=70
70 % 10 = 0
So 201162-53-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H20N2O2/c1-11(2,3)15-10(14)13-6-8-4-5-9(7-13)12-8/h8-9,12H,4-7H2,1-3H3
201162-53-0Relevant articles and documents
Substituted diazabicycloalkane derivatives
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Page/Page column 35, (2010/02/11)
Compounds of formula (I) [in-line-formulae]Z-Ar1—Ar2??(I) [/in-line-formulae] wherein Z is a diazabicyclic amine, Ar1 is a 5- or 6-membered aromatic ring, and Ar2 is selected from the group consisting of an unsubstituted or substituted 5- or 6-membered heteroaryl ring; unsubstituted or substituted bicyclic heteroaryl ring; 3,4-(methylenedioxy)phenyl; carbazolyl; tetrahydrocarbazolyl; naphthyl; and phenyl; wherein the phenyl is substituted with 0, 1, 2, or 3 substituents in the meta- or para-positions. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions comprising compounds of formula (I) and methods for using such compounds and compositions.
Novel amides useful for treating pain
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Page/Page column 19, (2010/02/11)
The present invention relates to compounds of formula (I-VII) or a pharmaceutically acceptable salt or prodrug thereof, in which A, L, R6, R7 and R8 are defined herein. The present invention also relates to methods of trating pain using these compounds and pharmaceutical compositions including these compounds.