201165-99-3

Basic information

• Product Name: 1-[(2R,5S)-5-{[(8-methoxy-2-oxido-4H-1,3,2-benzodioxaphosphinin-2-yl)oxy]methyl}-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
• CAS NO: 201165-99-3
• Molecular Formula: C₁₈H₁₉N₂O₈P
• Molecular Weight: 422.3258
• Mol File: 201165-99-3.mol
• Article Data: 1

Chemical Properties

• Density: 1.5g/cm³
• Refractive Index: 1.621
• CAS DataBase Reference: 1-[(2R,5S)-5-{[(8-methoxy-2-oxido-4H-1,3,2-benzodioxaphosphinin-2-yl)oxy]methyl}-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(2R,5S)-5-{[(8-methoxy-2-oxido-4H-1,3,2-benzodioxaphosphinin-2-yl)oxy]methyl}-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione(201165-99-3)
• EPA Substance Registry System: 1-[(2R,5S)-5-{[(8-methoxy-2-oxido-4H-1,3,2-benzodioxaphosphinin-2-yl)oxy]methyl}-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione(201165-99-3)

Safety Data

• Hazardous Substances Data: 201165-99-3(Hazardous Substances Data)

Usage

Chemical structure

The compound has a complex structure with a pyrimidine core, a furan ring, and a phosphorous-containing group attached.

Stereochemistry

The compound has a specific configuration of the carbon atoms in the furan ring, with a 2R,5S configuration.

Functional groups

The compound contains a methoxy group (-OCH3) and an oxido group (=O), adding complexity to its structure.

Phosphorus-containing group

The presence of a phosphorus-containing group suggests potential reactivity and the ability to participate in various chemical reactions.

Potential applications

Due to its unique and intricate structure, the compound may have implications in various chemical and biological processes.

Molecular weight

The molecular weight of the compound is approximately 380.26 g/mol.

Appearance

The compound is likely to be a solid, although its exact appearance (e.g., color, crystal structure) is not provided in the material.

Solubility

The solubility of the compound is not provided in the material, but it may be influenced by its polar and nonpolar components, as well as its molecular weight.

Upstream product

• 195885-76-8 3-methoxysalicylchlorophosphane 
• 877-22-5 3-methoxysalicylic acid 
• 4383-05-5 2-hydroxy-3-methoxybenzyl alcohol 
• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 

Downstream Products

• 4383-05-5 2-hydroxy-3-methoxybenzyl alcohol 

Relevant articles and documents

Cyclo-saligenyl-2',3'-dideoxy-2',3' didehydroythymidinemonophosphate (cyclosal-d4TMP) - A new pro-nucleotide approach

The synthesis of cycloSal-d4TMP 3a-g as new pro-nucleotide approach for d4TMP 2 is described. Phosphotriesters 3 release the d4TMP 2 selectively by a controlled, chemically induced tandem reaction. CycloSa1-phosphotriesters 3 exhibited high biological activity against HIV-1/HIV-2 in CEM cells which was completely retained in CEM TK- cells.