20129-56-0

Basic information

• Product Name: 3,3-Dimethyl-5-oxopyrrolidin-1-ylpentansaeure
• Synonyms: 3,3-Dimethyl-5-oxopyrrolidin-1-ylpentansaeure
• CAS NO: 20129-56-0
• Molecular Weight: 213.277
• Mol File: 20129-56-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,3-Dimethyl-5-oxopyrrolidin-1-ylpentansaeure(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-Dimethyl-5-oxopyrrolidin-1-ylpentansaeure(20129-56-0)
• EPA Substance Registry System: 3,3-Dimethyl-5-oxopyrrolidin-1-ylpentansaeure(20129-56-0)

Safety Data

• Hazardous Substances Data: 20129-56-0(Hazardous Substances Data)

Upstream product

• 3357-16-2 5,5-dimethyl-3-(1-pyrrolidinyl)-2-cyclohexen-1-one 

Relevant articles and documents

Aminoreductones - Investigations on species containing the carbon arrangement of dintedone and secondary amines as building blocks

The ozonation of 3-(sec-amino)-5,5-dimethylcyclohex-2-en-1-ones 4 was compared with the corresponding acyloxylations by diacylperoxides 5, making accessible 3-(sec-amino)-reductones 9. Both types of oxygenation also led to higher-oxygenated six-ring carbocyclic products (7, 8, 17), ozonation being a minor reaction path, in addition to C=C cleavage. The corresponding 2-(sec-amino)reductones 34 were generated via aminolysis of the iodonium intermediate 44 (Scheme 13), and their reductive behavior against t-BuOCl and 3-chloroperbenzoic acid (MCPBA) as oxidizing agents was compared. Attempts to generate the corresponding reductone 5,5-dimethyl-2,3-dimorpholin-4-ylcyclohex- 2-en-1-one (45) were unsuccessful (Scheme 13). Instead, the corresponding iodonium intermediate 44 suffered a Favorskii-like regioselective ring contraction during aminolysis, followed by autoxidation. These unexpected reactions were confirmed by separate experiments.