20143-48-0

Basic information

• Product Name: (2,6-DIMETHYLPHENOXY)-ACETYLCHLORIDE
• Synonyms: (2,6-DIMETHYLPHENOXY)-ACETYLCHLORIDE
• CAS NO: 20143-48-0
• Molecular Formula: C₁₀H₁₁ClO₂
• Molecular Weight: 198.64614
• Product Categories: Aromatics Compounds;Aromatics
• Mol File: 20143-48-0.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• Solubility: Acetone, Chloroform, Dichloromethane
• CAS DataBase Reference: (2,6-DIMETHYLPHENOXY)-ACETYLCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (2,6-DIMETHYLPHENOXY)-ACETYLCHLORIDE(20143-48-0)
• EPA Substance Registry System: (2,6-DIMETHYLPHENOXY)-ACETYLCHLORIDE(20143-48-0)

Safety Data

• Hazardous Substances Data: 20143-48-0(Hazardous Substances Data)

Usage

Description

(2,6-DIMETHYLPHENOXY)-ACETYLCHLORIDE, with the chemical name (2,6-Dimethylphenoxy)acetyl Chloride and CAS number 20143-48-0, is a light-yellowish oil compound that is useful in organic synthesis. It is characterized by its unique chemical structure, which includes a 2,6-dimethylphenoxy group attached to an acetyl chloride moiety.

Uses

Used in Organic Synthesis:
(2,6-DIMETHYLPHENOXY)-ACETYLCHLORIDE is used as a reagent in organic synthesis for various chemical reactions. Its unique structure allows it to act as a versatile building block in the synthesis of complex organic molecules, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (2,6-DIMETHYLPHENOXY)-ACETYLCHLORIDE is used as an intermediate in the synthesis of various drug molecules. Its ability to form stable bonds with other chemical entities makes it a valuable component in the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
(2,6-DIMETHYLPHENOXY)-ACETYLCHLORIDE is also used in the agrochemical industry as a precursor for the synthesis of various agrochemicals, such as pesticides and herbicides. Its chemical properties enable it to be incorporated into molecules that can effectively control pests and weeds in agricultural settings.
Used in Specialty Chemicals:
In the specialty chemicals industry, (2,6-DIMETHYLPHENOXY)-ACETYLCHLORIDE is used as a key component in the production of various specialty chemicals, such as dyes, fragrances, and other fine chemicals. Its unique structure and reactivity make it suitable for creating high-value products with specific applications.

Upstream product

• 6279-47-6 ethyl 2-(2,6-dimethylphenoxy)acetate 
• 32133-94-1 2,6-Dimethylphenylmercaptoessigsaeure 
• 576-26-1 2.6-dimethylphenol 
• 13335-71-2 2-(2,6-dimethylphenoxy)acetic acid 

Downstream Products

• 898254-22-3 N-((2S,4S,5S)-5-(dibenzylamino)-4-hydroxy-1,6-diphenylhexan-2-yl)-2-(2,6-dimethylphenoxy)acetamide 
• 192725-17-0 lopinavir 
• 192725-45-4 (2S,3S,5S)-2-(2,6-dimethylphenoxyacetyl)amino-3-hydroxy-5-(t-butyloxycarbonylamino)-1,6-diphenylhexane 

Relevant articles and documents

Synthesis and characterization of novel analogues of lopinavir

The present work describes the identification, origin, synthesis, characterization and control of four novel analogues of lopinavir viz. leucine analogue of lopinavir, isoleucine analogue of lopinavir, methyl analogue of lopinavir and dihydroxy analogue of lopinavir.

Molecular tools that block maturation of the nuclear lamin A and decelerate cancer cell migration

Lamin A contributes to the structure of nuclei in all mammalian cells and plays an important role in cell division and migration. Mature lamin A is derived from a farnesylated precursor protein, known as prelamin A, which undergoes post-translational cleavage catalyzed by the zinc metalloprotease STE24 (ZPMSTE24). Accumulation of farnesylated prelamin A in the nuclear envelope compromises cell division, impairs mitosis and induces an increased expression of inflammatory gene products. ZMPSTE24 has been proposed as a potential therapeutic target in oncology. A library of peptidomimetic compounds were synthesized and screened for their ability to induce accumulation of prelamin A in cancer cells and block cell migration in pancreatic ductal adenocarcinoma cells. The results of this study suggest that inhibitors of lamin A maturation may interfere with cell migration, the biological process required for cancer metastasis.

DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE

The subject of the invention is a group of new derivatives of aminoalkaπols, more specifically [(phenoxy)alkyl]aminoalkanols and [(phenoxy)acyl)aminoalkanols, their method of obtaining and their use for production of a medicine which is used in the prophylaxis, prevention and/or treatment of diseases or symptoms having neurological background and for production of a medicine with anticonvulsant activity, which is used in seizures of various origin, also in the limbic system, in myoclonic or sound-induced seizures, in psychomotor epilepsy, as well as in relieving neuropathic or inflammatory pain.