201809-20-3 Usage
Description
4-(5-Ethoxycarbonyl-pyridin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester is a chemical compound that belongs to the class of piperazine carboxylic acid derivatives. It is an ester derivative of piperazine-1-carboxylic acid, with a tert-butyl group attached to the carboxylic acid functional group. 4-(5-ETHOXYCARBONYL-PYRIDIN-2-YL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is characterized by its ethoxycarbonyl-pyridin-2-yl and piperazine moieties, which are important structural elements that can potentially influence the biological activity and pharmacokinetic properties of the resulting compounds. The tert-butyl ester group provides stability and solubility to the molecule, making it a valuable intermediate in chemical synthesis and drug development.
Uses
Used in Pharmaceutical Industry:
4-(5-Ethoxycarbonyl-pyridin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester is used as a building block in the synthesis of various bioactive compounds and drug molecules. Its unique structural elements, including the ethoxycarbonyl-pyridin-2-yl and piperazine moieties, contribute to the development of pharmaceuticals with enhanced biological activity and improved pharmacokinetic properties. The tert-butyl ester group also plays a crucial role in providing stability and solubility, which are essential for effective chemical synthesis and drug development processes.
Check Digit Verification of cas no
The CAS Registry Mumber 201809-20-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,8,0 and 9 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 201809-20:
(8*2)+(7*0)+(6*1)+(5*8)+(4*0)+(3*9)+(2*2)+(1*0)=93
93 % 10 = 3
So 201809-20-3 is a valid CAS Registry Number.
201809-20-3Relevant articles and documents
Structure-guided optimization of quinoline inhibitors of Plasmodium N-myristoyltransferase
Goncalves, Victor,Brannigan, James A.,Laporte, Alice,Bell, Andrew S.,Roberts, Shirley M.,Wilkinson, Anthony J.,Leatherbarrow, Robin J.,Tate, Edward W.
supporting information, p. 191 - 197 (2017/02/05)
The parasite Plasmodium vivax is the most widely distributed cause of recurring malaria. N-Myristoyltransferase (NMT), an enzyme that catalyses the covalent attachment of myristate to the N-terminal glycine of substrate proteins, has been described as a p
TROPANE COMPOUNDS
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Page/Page column 374, (2009/05/30)
A compound according to Formula I or II: (I) or (II) wherein R1, R1b, R2, L1, and L2 and L2b are as defined in the specification, pharmaceutical compositions thereof, and methods of use thereof.
