20229-41-8

Basic information

• Product Name: l-menthyl phenylglyoxylate
• Synonyms: l-menthyl phenylglyoxylate
• CAS NO: 20229-41-8
• Molecular Weight: 288.387
• Mol File: 20229-41-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: l-menthyl phenylglyoxylate(CAS DataBase Reference)
• NIST Chemistry Reference: l-menthyl phenylglyoxylate(20229-41-8)
• EPA Substance Registry System: l-menthyl phenylglyoxylate(20229-41-8)

Safety Data

• Hazardous Substances Data: 20229-41-8(Hazardous Substances Data)

Upstream product

• 25726-04-9 phenylglyoxylyl chloride 
• 2216-51-5 (-)-menthol 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 89-78-1 menthol 
• 611-73-4 Benzoylformic acid 
• 2085-26-9 bis[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl]oxalate 
• 62977-82-6 benzyl oxo(phenyl)acetate 
• 6405-71-6 Oxo-phenyl-acetic acid 1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 170157-72-9 (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 2-diazo-2-phenylacetate 
• 26171-78-8 (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 2-phenylacetate 
• 103-82-2 phenylacetic acid 

Downstream Products

• 4166-98-7 4-methyl-benzilic acid 
• 170157-70-7 (1R,2S,5R)-Menthyl 2-oxophenylacetate tosylhydrazone 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 57133-41-2 (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-hydroxy-2-phenylbutanoate 
• 57138-98-4 menthyl 2-hydroxy-2-phenylbutanoate 
• 1152438-24-8 (-)-Menthyl hydroxyphenylacetate 
• 6405-71-6 Oxo-phenyl-acetic acid 1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 62977-82-6 benzyl oxo(phenyl)acetate 
• 96606-31-4 Oxo-phenyl-acetic acid 2-methyl-butyl ester 
• 127559-51-7 acide phenyl-2 hydroxy-2 octanoique 
• 127559-50-6 acide phenyl-2 hydroxy-2 hexanoique 
• 97690-17-0 acide phenyl-2 hydroxy-2 methyl-4 pentanoique 
• 117195-37-6 acide phenyl-2 hydroxy-2 octanoique 
• 117195-36-5 (R)-2-Phenyl-2-hydroxyhexanoic acid 

Relevant articles and documents

Photoinduced Diverse Reactivity of Diazo Compounds with Nitrosoarenes

A diverse reactivity of diazo compounds with nitrosoarene in an oxygen-transfer process and a formal [2 + 2] cycloaddition is reported. Nitosoarene has been exploited as a mild oxygen source to oxidize an in situ generated carbene intermediate under visible-light irradiation. UV-light-mediated in situ generated ketenes react with nitosoarenes to deliver oxazetidine derivatives. These operationally simple processes exemplify a transition-metal-free and catalyst-free protocol to give structurally diverse α-ketoesters or oxazetidines.

Selective Formation of Functionalized α-Quaternary Malononitriles toward 5,5-Disubstituted Pyrrolopyrimidinones

A modular, selective approach to complex α-tertiary substituted malononitriles is reported. The method takes advantage of β-ester-substituted α,α-dinitrile alkenes as highly reactive, chemoselective electrophiles for 1,4-additions with organometallic nucleophiles to produce functionally and sterically dense all-carbon quaternary centers. In the presence of a chiral ester auxiliary bearing an aromatic ring, the 1,4-addition occurs with good to excellent selectivity due to favorable cation-π interactions. The highly functionalized malononitriles represent versatile building blocks and can be applied toward efficient, highly selective syntheses of 5,5-disubstituted pyrrolopyrimidinones.

Dimethylzinc-mediated addition of alkenylzirconocenes to α-keto and α-imino esters

(Matrix presented) Hydrozirconation of alkynes followed by in situ transmetalation to dimethylzinc and 1,2-addition to activated ketones and N-diphenylphosphinoylimines leads to tertiary allylic alcohols and amines in high overall yield. With 8-phenylmenthol as the chiral auxiliary, si-face attack proceeds in good to excellent diastereoselectivities.