202409-40-3 Usage
Description
Etoricoxib hydrochloride is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain and inflammation in conditions such as arthritis. It works by inhibiting the production of prostaglandins, which are natural substances in the body that cause pain and inflammation. By reducing the levels of prostaglandins, etoricoxib hydrochloride helps to alleviate symptoms such as joint pain, swelling, and stiffness.
Uses
Used in Pharmaceutical Industry:
Etoricoxib hydrochloride is used as an anti-inflammatory and analgesic agent for the treatment of conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout. It is effective in reducing pain, inflammation, and improving joint function in these conditions.
Used in Pain Management:
Etoricoxib hydrochloride is used as a pain reliever for acute and chronic pain conditions, including post-operative pain, dental pain, and menstrual pain. It provides effective pain relief by reducing inflammation and prostaglandin production.
Used in Inflammatory Conditions:
Etoricoxib hydrochloride is used as an anti-inflammatory agent for the treatment of various inflammatory conditions, such as tendinitis, bursitis, and soft tissue injuries. It helps to reduce inflammation, swelling, and pain associated with these conditions.
However, it is important to note that etoricoxib hydrochloride, like other NSAIDs, can carry potential risks and side effects, including gastrointestinal bleeding, heart problems, and kidney issues. Therefore, it should be used with caution and under the supervision of a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 202409-40-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,2,4,0 and 9 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 202409-40:
(8*2)+(7*0)+(6*2)+(5*4)+(4*0)+(3*9)+(2*4)+(1*0)=83
83 % 10 = 3
So 202409-40-3 is a valid CAS Registry Number.
202409-40-3Relevant articles and documents
Method for preparing etoricoxib
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Paragraph 0052; 0053; 0054; 0058; 0059; 0062; 0063, (2017/08/02)
The invention discloses a method for preparing etoricoxib, and provides a method for preparing etoricoxib I. The method comprises the following step: performing neutralization reaction on hydrohaloride of the etoricoxib I and alkali in a halogenated hydrocarbon solvent to obtain the etoricoxib I, wherein X is halogen. The preparation method is mild in reaction condition, simple and safe in operation and high in yield, no special purification equipment is required, column chromatography separation operation in a posttreatment process is avoided, and the prepared etoricoxib is high in purity (the purity is equal to or higher than 99.5 percent, the content of all impurities is equal to or lower than 0.10 percent, and a raw medicament standard can be met), low in cost and suitable for industrial production.
Substituted pyridines as selective cyclooxygenase-2 inhibitors
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, (2008/06/13)
The invention encompasses the novel compound of Formula I as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. STR1 The invention also encompasses certain pharmaceutical compositions for treatment of COX-2 mediated diseases comprising compounds of Formula I.