20245-85-6

Basic information

• Product Name: 9-vinyl-9H-purin-6-amine
• Synonyms: 9-vinyl-9H-purin-6-amine;Adefovir Dipivoxil Impurity 10
• CAS NO: 20245-85-6
• Molecular Formula: C₇H₇N₅
• Molecular Weight: 161.16398
• EINECS: -0
• Mol File: 20245-85-6.mol
• Article Data: 8

Chemical Properties

• Melting Point: 198 °C
• Boiling Point: 409.6±48.0 °C(Predicted)
• Appearance: /
• Density: 1.47±0.1 g/cm3(Predicted)
• PKA: 3.90±0.10(Predicted)
• CAS DataBase Reference: 9-vinyl-9H-purin-6-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 9-vinyl-9H-purin-6-amine(20245-85-6)
• EPA Substance Registry System: 9-vinyl-9H-purin-6-amine(20245-85-6)

Safety Data

• Hazardous Substances Data: 20245-85-6(Hazardous Substances Data)

Upstream product

• 75-07-0 acetaldehyde 
• 66224-66-6 adenine 
• 15816-12-3 6-chloro-9-vinylpurine 
• 4005-49-6 N-benzoyladenine 
• 79293-84-8 N-(tert-butyldimethylsilyl)phthalimide 
• 68217-74-3 9‐(2‐bromoethyl)‐9H‐purin‐6‐amine 
• 106-93-4 ethylene dibromide 
• 19255-48-2 9-(2-chloroethyl)adenine 

Downstream Products

• 1080634-11-2 9-{(2R,3aR,4R,5R,6R)-4,5-bis(benzyloxy)-6[(benzyloxy)methyl]hexahydropyrrolo[1,2-b]isoxazol-2-yl}adenine 

Relevant articles and documents

Specific base recognition of oligodeoxynucleotides by capillary affinity gel electrophoresis using polyacrylamide-poly(9-vinyladenine) conjugated gel

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UNSATURATED HETEROCYCLIC DERIVATIVES

This invention relates to compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.

Synthesis and study of a new adenine-acridine tandem, inhibitor of exonuclease III

A new heterodimer adenine-chain-acridine containing a mixed amido-guanidinium linker chain was synthesized. To achieve the synthesis a new method of introduction of aminoalkyl chain at position 9 of adenine was designed. The heterodimer interacts specifically with the abasic sites in DNA and inhibits the major base excision repair enzyme in Escherichia coli, Exonuclease III. (C) 2000 Elsevier Science Ltd. All rights reserved.