202462-83-7Relevant articles and documents
Visual detection of copper(II) by azide- and alkyne-functionalized gold nanoparticles using click chemistry
Zhou, Yang,Wang, Shixing,Zhang, Ke,Jiang, Xingyu
, p. 7454 - 7456 (2008)
(Figure Presented) Just one click, and the color's gone: In the presence of Cu2+ with sodium ascorbate as a reductant, gold nanoparticles that have azide- and alkyne-terminated groups undergo aggregation as the result of CuI-catalyzed click chemistry. This process can be monitored by eye without the aid of instruments (NPs=nanoparticles).
Formation of carbohydrate-functionalised polystyrene and glass slides and their analysis by MALDI-TOF MS
Weissenborn, Martin J.,Wehner, Johannes W.,Gray, Christopher J.,Sardzik, Robert,Eyers, Claire E.,Lindhorst, Thisbe K.,Flitsch, Sabine L.
, p. 753 - 762 (2012)
Glycans functionalised with hydrophobic trityl groups were synthesised and adsorbed onto polystyrene and glass slides in an array format. The adsorbed glycans could be analysed directly on these minimally conducting surfaces by MALDI-TOF mass spectrometry
NANOPARTICLES FOR DIAGNOSIS AND DRUG DELIVERY
-
Page/Page column 44, (2017/04/11)
The present invention relatesto a nanoparticle having a size comprised from 2 to 300 nm comprising: (i) a core comprising on its surface a noble metal selected from gold, silver or platinum, and (ii) an optionally positively charged amphiphilic linker comprising a hydrophobic C1-C20 alkyl thiolate moiety and a hydrophilic moietywhich is optionally hydrophilic positively charged. The invention also provides nanovectors comprising the nanoparticles of the invention and a compound of interest,such as a pharmaceutically active agent, in particular an anti-tumoral agent. Also provided are nanoparticles and nanovectors as defined above for diagnosis or for the prevention and/or treatment of a disease, in particular cancer.
