202532-13-6Relevant articles and documents
The synthesis of di(hydroxyalkyl) substituted bicyclic guanidines
Madder, A.,Muenster, I.,Rolle, U.,Clercq, P. J. De
, p. 613 - 622 (2007/10/03)
The synthesis of the enantiomerically pure bicyclic guanidines 3a and 3b is described.The convergent strategy is based on methodology developed by Schmidtchen.The therefore required amine components 6 and 9 obtained from methionine and L-glutamic acid, respectively.