203172-89-8

Basic information

• Product Name: 3-Trifluoromethyl-benzoic acid (2S,3R,4R,5R)-4-benzoyloxy-5-benzoyloxymethyl-2-(diisopropoxy-phosphorylmethoxy)-tetrahydro-furan-3-yl ester
• Synonyms: 3-Trifluoromethyl-benzoic acid (2S,3R,4R,5R)-4-benzoyloxy-5-benzoyloxymethyl-2-(diisopropoxy-phosphorylmethoxy)-tetrahydro-furan-3-yl ester
• CAS NO: 203172-89-8
• Molecular Weight: 708.622
• Mol File: 203172-89-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Trifluoromethyl-benzoic acid (2S,3R,4R,5R)-4-benzoyloxy-5-benzoyloxymethyl-2-(diisopropoxy-phosphorylmethoxy)-tetrahydro-furan-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Trifluoromethyl-benzoic acid (2S,3R,4R,5R)-4-benzoyloxy-5-benzoyloxymethyl-2-(diisopropoxy-phosphorylmethoxy)-tetrahydro-furan-3-yl ester(203172-89-8)
• EPA Substance Registry System: 3-Trifluoromethyl-benzoic acid (2S,3R,4R,5R)-4-benzoyloxy-5-benzoyloxymethyl-2-(diisopropoxy-phosphorylmethoxy)-tetrahydro-furan-3-yl ester(203172-89-8)

Safety Data

• Hazardous Substances Data: 203172-89-8(Hazardous Substances Data)

Upstream product

• 24630-68-0 diisopropyl hydroxymethylphosphonate 
• 145828-13-3 α-D-1,3,5-tri-O-benzoyl-2-O-[3-(trifluoromethyl)benzoyl]ribofuranose 
• 203172-88-7 3-Trifluoromethyl-benzoic acid (2R,3R,4R,5R)-2-acetoxy-4-benzoyloxy-5-benzoyloxymethyl-tetrahydro-furan-3-yl ester 
• 454-92-2 3-(trifluoromethyl)benzoic acid 
• 22224-41-5 1,3,5-tri-O-benzoyl-α-D-ribofuranoside 

Downstream Products

• 203172-83-2 (diisopropylphosphonyl)methyl 3,5-bis-O-benzoyl-2-deoxy-β-D-erythro-pentofuranoside 

Relevant articles and documents

Synthesis of phosphonate analogues of 2-deoxyribose-1-phosphate

Phosphonate derivatives of 2-deoxyribose have been synthesized for the first time, by Lewis acid-mediated reaction of glycosyl donors with diisopropylhydroxymetylphosphonate for compounds 2 or with triisopropyl phosphite for compounds 3. Although, the selectivity of the reaction was moderate, in both cases the α-glycosides were predominantly obtained.