203180-34-1

Basic information

• Product Name: 4-{2-[4-(benzo[1,3]dioxole-5-sulfonyl)-phenyl]-[1,3]dioxolan-2-yl}-[1,4']bipiperidinyl-1'-carboxylic acid ethyl ester
• CAS NO: 203180-34-1
• Molecular Weight: 572.679
• Mol File: 203180-34-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-{2-[4-(benzo[1,3]dioxole-5-sulfonyl)-phenyl]-[1,3]dioxolan-2-yl}-[1,4']bipiperidinyl-1'-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{2-[4-(benzo[1,3]dioxole-5-sulfonyl)-phenyl]-[1,3]dioxolan-2-yl}-[1,4']bipiperidinyl-1'-carboxylic acid ethyl ester(203180-34-1)
• EPA Substance Registry System: 4-{2-[4-(benzo[1,3]dioxole-5-sulfonyl)-phenyl]-[1,3]dioxolan-2-yl}-[1,4']bipiperidinyl-1'-carboxylic acid ethyl ester(203180-34-1)

Safety Data

• Hazardous Substances Data: 203180-34-1(Hazardous Substances Data)

Upstream product

• 203186-31-6 4-[4-(benzo[1,3]dioxol-5-ylsulfanyl)-benzoyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 203186-32-7 [4-(benzo[1,3]dioxol-5-ylsulfanyl)-phenyl]-piperidin-4-yl-methanone 
• 160296-40-2 tert-butyl 1-[4-(4-fluorobenzoyl)piperidin-1-yl]carboxylate 
• 29976-53-2 N-ethoxycarbonyl-4-piperidone 
• 56346-57-7 (4-fluorophenyl)-piperidin-4-ylmethanone 

Relevant articles and documents

Benzylidene ketal derivatives as M2 muscarinic receptor antagonists

Benzylidene ketal derivatives were investigated as selective M2 receptor antagonists for the treatment of Alzheimer's disease. Compound 10 was discovered to have subnanomolar M2 receptor affinity and 100-fold selectivity against other muscarinic receptors. Also, 10 demonstrated in vivo efficacy in rodent models of muscarinic activity and cognition. (C) 2000 Elsevier Science Ltd.