20331-32-2

Basic information

• Product Name: N-<4-(2-methylpropyl)phenyl>acetamide
• Synonyms: N-<4-(2-methylpropyl)phenyl>acetamide
• CAS NO: 20331-32-2
• Molecular Weight: 191.273
• Mol File: 20331-32-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-<4-(2-methylpropyl)phenyl>acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-<4-(2-methylpropyl)phenyl>acetamide(20331-32-2)
• EPA Substance Registry System: N-<4-(2-methylpropyl)phenyl>acetamide(20331-32-2)

Safety Data

• Hazardous Substances Data: 20331-32-2(Hazardous Substances Data)

Upstream product

• 30090-17-6 4-isobutylaniline 
• 108-24-7 acetic anhydride 
• 538-93-2 1-phenyl-2-methylpropane 
• 74305-51-4 4'-(2-methylpropyl)acetophenone oxime 
• 10342-60-6 1-isobutyl-4-nitrobenzene 
• 100-86-7 2-Methyl-1-phenyl-2-propanol 
• 588-47-6 N-isobutylaniline 

Downstream Products

• 79069-39-9 2-amino-5-(2-methylpropyl)benzoic acid 
• 79069-36-6 N-<2-bromo-4-(2-methylpropyl)phenyl>acetamide 

Relevant articles and documents

Radical Beckmann Rearrangement and Its Application in the Formal Total Synthesis of Antimalarial Natural Product Isocryptolepine via C-H Activation

The Beckmann rearrangement of ketoximes, mediated by ammonium persulfate-dimethyl sulfoxide as a reagent, has been achieved under neutral conditions. Based on the radical trapping and 18O-labeling experiments, the transformation follows a mechanism involving a radical pathway. The scope and generality of the developed protocol has been demonstrated by 19 examples. The developed protocol and Pd-catalyzed intramolecular double C-H activation were used as key steps in the formal total synthesis of antimalarial natural product isocryptolepine.