20348-09-8Relevant articles and documents
SUBSTITUTED HETEROCYCLIC COMPOUNDS AS CRAC MODULATORS
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, (2016/06/13)
The invention relates to compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine for the treatment of diseases, disorders associated with the modulation of calcium release-activated calcium (CRAC) channel. The invention also relates to pharmaceutical compositions containing such compounds in treating diseases disorders associated with calcium release-activated calcium (CRAC) channel modulators. wherein, ring D is Formula (a) or Formula (b): A and B, which may be same or different, are independently CR3 or N; Y is CR3 or N; L is selected from —NR2C(O)—, —C(O)NR2— and —NR2CRaRb—; Ra and Rb are independently hydrogen, halogen or substituted or unsubstituted alkyl; ring E is selected from the Formula (i) to (vii).
A 2-amino-thiazole compounds (by machine translation)
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Paragraph 0605-0607, (2016/10/08)
The present invention relates to the technical field of pharmaceutical chemistry, particularly relates to a 2-amino thiazole compound or its pharmaceutically acceptable salts, its preparation method, and pharmaceutical compositions containing such compounds and its application in the preparation of antineoplastic. (by machine translation)
Short and efficient synthesis of oxazinone-and thiazinone-containing bicyclic heteroaromatic aldehydes
Hameed P., Shahul,Shanbhag, Gajanan,Shinde, Vikas,Chinnapattu, Murugan,Manjrekar, Praveena,Puttur, Jayashree,Patil, Vikas,Ugarkar, Bheemarao
, p. 3315 - 3321 (2013/10/01)
Short and efficient route for the synthesis of oxazinone-and thiazinone-containing bicyclic heteroaromatic aldehydes, which involves the key step of palladium-catalyzed reductive carbonylation, is described. Overall routes for the synthesis of these aldehydes are short, versatile, and scalable with good yields of the product. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications for the following free supplemental resource(s): Full experimental and spectral details.]