20364-37-8

Basic information

• Product Name: 2(1H)-Pyridinone, 4-methyl-6-phenyl-
• CAS NO: 20364-37-8
• Molecular Formula: C12H11NO
• Molecular Weight: 185.225
• Mol File: 20364-37-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2(1H)-Pyridinone, 4-methyl-6-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Pyridinone, 4-methyl-6-phenyl-(20364-37-8)
• EPA Substance Registry System: 2(1H)-Pyridinone, 4-methyl-6-phenyl-(20364-37-8)

Safety Data

• Hazardous Substances Data: 20364-37-8(Hazardous Substances Data)

Upstream product

• 7664-93-9 sulfuric acid 
• 113123-56-1 2-hydroxy-4-methyl-6-phenyl-nicotinic acid ethyl ester 
• 74547-15-2 2-amino-4-methyl-6-phenyl-nicotinic acid 
• 845716-85-0 2-amino-4-methyl-6-phenyl-nicotinamide 
• 52117-38-1 4-phenyl-4-chloro-2-butanone 
• 487016-54-6 2-chloro-N-(3-oxo-1-phenyl-butyl)-acetamide 
• 5977-14-0 acetoacetamido 
• 98-86-2 acetophenone 
• 93-91-4 1-phenylbutan-1,3-dione 
• 82417-99-0 2-Amino-4-methyl-6-phenyl-3-pyridincarbonsaeure-ethylester 
• 109-77-3 malononitrile 
• 33899-65-9 2-hydroxy-4-methyl-6-phenyl-nicotinic acid 

Relevant articles and documents

N-3-oxoalkylamides and -thioamides in the synthesis of heterocyclic compounds. 7*. Study of the cyclization of N-(3-oxoalkyl)amides of tosylacetic acid

Alkyl-substituted N-(3-oxoalkyl)amides of tosylacetic acid are cyclized under the action of bases with the formation of 3-tosyl-3,6-dihydropyridin-2(1H) -ones. In the presence of a phenyl substituent at position C(1) of the 3-oxoalkyl chain the

Process for the production of 6-substituted 4-methyl-2-pyridones

Process for the production of 6-substituted-4-methyl-2-pyridones having the formula: STR1 wherein R is a branched or unbranched alkyl group, a halogenated branched or unbranched alkyl group or a substituted or unsubstituted aryl group. Senecioic acid amide having the formula: STR2 is reacted in a solvent at an elevated temperature in the presence of a Lewis acid (as a catalyst) with an acyl chloride having the formula: STR3 wherein R has the same meaning as above. The reaction mixture is subsequently placed in an aqueous phase for hydrolysis. The 6-substituted-4-methyl-2-pyridone is separated by extraction through the buffering of the reaction mixture at a pH of 4 to 5.

On the knowledge of acetylenecarboxylic acids. 14. alpha-Pyrone from 3-hydroxy-4-alkynoic acid esters.

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