20365-21-3

Basic information

• Product Name: methyl 3-oxo-3-phenylpropanedithioate
• Synonyms: methyl 3-oxo-3-phenylpropanedithioate
• CAS NO: 20365-21-3
• Molecular Weight: 210.321
• Mol File: 20365-21-3.mol
• Article Data: 15

Chemical Properties

• Melting Point: 57-58 °C
• Boiling Point: 348.8±25.0 °C(Predicted)
• Density: 1.216±0.06 g/cm3(Predicted)
• CAS DataBase Reference: methyl 3-oxo-3-phenylpropanedithioate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-oxo-3-phenylpropanedithioate(20365-21-3)
• EPA Substance Registry System: methyl 3-oxo-3-phenylpropanedithioate(20365-21-3)

Safety Data

• Hazardous Substances Data: 20365-21-3(Hazardous Substances Data)

Upstream product

• 13636-88-9 3,3-bis(methylthio)-1-phenylprop-2-en-1-one 
• 2314-48-9 (S,S)-dimethyl trithiocarbonate 
• 98-86-2 acetophenone 

Downstream Products

• 83392-35-2 methyl 3-(4-methylphenyl)-3-oxopropanedithioate 
• 843640-82-4 methyl 2-[(3-oxo-3-phenylpropanthioyl)amino]acetate 
• 80967-26-6 1,5-diphenyl-3-(methylthio)-1H-pyrazole 
• 50609-82-0 [5-(methylsulfanyl)-3-phenyl-2-thienyl](phenyl)-methanone 
• 1038750-48-9 1-[5-(methylsulfanyl)-3-phenyl-2-thienyl]-1-ethanone 
• 1312414-02-0 3-benzoyl-4-(4-fluorophenyl)-2-methylsulfanyl-4,6,7,8-tetrahydrothiochromen-5-one 
• 1312414-05-3 3-benzoyl-7,7-dimethyl-2-methylsulfanyl-4-(3-nitrophenyl)-4,6,7,8-tetrahydrothiochromen-5-one 
• 1312414-03-1 3-benzoyl-7,7-dimethyl-2-methylsulfanyl-4-(4-nitrophenyl)-4,6,7,8-tetrahydrothiochromen-5-one 
• 1312414-01-9 3-benzoyl-7,7-dimethyl-2-methylsulfanyl-4-phenyl-4,6,7,8-tetrahydrothiochromen-5-one 
• 1312414-04-2 3-benzoyl-4-(2,4-dichlorophenyl)-7,7-dimethyl-2-methylsulfanyl-4,6,7,8-tetrahydrothiochromen-5-one 
• 1312414-06-4 3-benzoyl-4-(4-bromophenyl)-7,7-dimethyl-2-methylsulfanyl-4,6,7,8-tetrahydrothiochromen-5-one 
• 1355657-31-6 2,4-diphenyl-4H-benzo[f]chromene-3-carbothioic acid O-methyl ester 
• 1355657-01-0 2-phenyl-4-p-tolyl-4H-benzo[f]chromene-3-carbothioicacid O-ethyl ester 
• 1355657-05-4 4-(4-fluorophenyl)-2-phenyl-4H-benzo[f]chromene-3-carbothioic acid O-ethyl ester 

Relevant articles and documents

A facile method for the synthesis of substituted 2-ylidene-1,3-oxathioles from acetophenones

Compounds incorporating 1,3-oxathiole moieties in their frameworks are biologically active. Active methylene ketones can be easily converted to the corresponding dithiocarboxylates by treatment with trithiocarbonate in the presence of sodium hydride. The

Access to Fully Substituted Thiazoles and 2,3-Dihydrothiazoles via Copper-Catalyzed [4 + 1] Heterocyclization of α-(N-Hydroxy/aryl)imino-β-oxodithioesters with α-Diazocarbonyls

An efficient chemoselective practical route to fully substituted thiazoles and 2,3-dihydrothiazoles has been devised by [4 + 1] heterocyclization of α-(N-hydroxy/aryl)imino-β-oxodithioesters with in situ generated Cu-carbenoids of diazocarbonyls. The α-(N-hydroxy/aryl)imino-β-oxodithioesters are readily accessible by the reaction of β-oxodithioesters with nitrous acid/nitrosoarenes. The overall transformation involves sequential N-O/C-N bonds cleavage followed by cascade C-N/C-S bonds formation in one-pot. This new strategy allows full control over the introduction of various sensitive functional groups at different positions of the thiazole ring, broadening the arsenal of synthetic methods to obtain such scaffolds.

A one-pot multicomponent synthesis of polysubstituted thiophenes via the reactions of an isocyanide, α-haloketones, and β-ketodithioesters in water

An efficient synthesis of polysubstituted thiophene derivatives is achieved via the multicomponent reaction of β-ketodithioesters, α-haloketones, and cyclohexylisocyanide in aqueous medium.